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10rx vs MD Trim Clinic

An in-depth comparison of two leading GLP-1 Providers

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10rx logo

10rx

7.0
★★★3.5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

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VS
MD Trim Clinic logo

MD Trim Clinic

5.8
★★☆☆2.9

Best for: DO+NP-led compounded sema/tirz clinic; tiered dosing, AZ+CA telehealth + in-office, B12 anti-nausea

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10rx and MD Trim Clinic are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts at $99.67/mo, and 10rx edges ahead overall (7.0 vs 5.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

MD Trim Clinic

Pricing not publicly listed.

What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

MD Trim Clinic

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Billed separately

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.0/10

Overall

MD Trim Clinic

5.8/10

Value25%

8.5A
vs
B
5.0

Effectiveness25%

7.0A
vs
B
6.5

User Experience15%

7.0A
vs
B
5.5

Trust & Safety15%

5.0A
vs
B
7.0

Accessibility10%

7.5A
vs
B
3.5

Support10%

6.0A
vs
B
7.0

Features & Coverage

Feature10rxMD Trim Clinic
Starting Price$99.67/mo
Features8 features8 features
States AvailableNot disclosed2
Compounded
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About MD Trim Clinic

MD Trim Clinic is a small physician-led practice in Phoenix, AZ and Novato, CA offering compounded semaglutide and tirzepatide via telehealth and in-person visits. Medications are dispensed from LegitScript-certified pharmacies with B12 added to reduce nausea, and programs are tiered by weekly dose (Level 1 / Level 2). Led by Dr. Brandon Shaw, D.O. and nurse practitioner Andrea Farris, N.P., the clinic includes free initial screening, physician-guided dosing titration, and ongoing team support.

Read our full MD Trim Clinic review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

MD Trim Clinic

What we like

  • Physician DO + NP team (Dr. Brandon Shaw, D.O. and Andrea Farris, N.P.) provides strong clinical oversight
  • Compounded meds from LegitScript-certified pharmacies — higher supply-chain trust than many small practices
  • Tiered dosing structure (Level 1 / Level 2) with B12 added to reduce nausea side effects
  • Both telehealth and in-person options available (AZ Phoenix and CA Novato offices)
  • Partnered mobile IV services available for enhanced nausea management and hydration support

Watch-outs

  • Pricing not disclosed publicly — must contact clinic for quotes, limiting upfront comparison shopping
  • Only AZ and CA confirmed — very limited geographic reach, excludes nearly all of the US
  • No LegitScript certification for the clinic itself (only pharmacy partners are LegitScript-certified)
  • Small practice with limited online presence and no published patient reviews or outcomes data
  • No labs, coaching, or monitoring protocols disclosed on the site

Our Verdict

Winner: 10rx

10rx edges out MD Trim Clinic with a higher overall score of 7.0/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. MD Trim Clinic remains a solid alternative, especially if you're looking for DO+NP-led compounded sema/tirz clinic; tiered dosing, AZ+CA telehealth + in-office, B12 anti-nausea.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose MD Trim Clinic if…

You want DO+NP-led compounded sema/tirz clinic; tiered dosing, AZ+CA telehealth + in-office, B12 anti-nausea.

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10rx vs MD Trim Clinic: FAQ

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