10rx vs Joi + Blokes
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons
Visit 10rx →
Joi + Blokes
Best for: GLP-1 alongside men's and women's hormone-health programs
Visit Joi + Blokes →10rx and Joi + Blokes are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Joi + Blokes starts lower at $99/mo versus $99.67/mo, and Joi + Blokes edges ahead overall (7.7 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Joi + Blokes
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Joi + Blokes
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Billed separately
Coaching
Included
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Joi + Blokes
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Joi + Blokes |
|---|---|---|
| Starting Price | $99.67/mo | ✓$99/mo |
| Features | ✓8 features | 7 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Joi + Blokes
Joi + Blokes is a hormone-first telehealth platform with parallel programs for women (Joi) and men (Blokes), now expanded to compounded GLP-1s for weight loss. The integrated hormone-plus-GLP-1 stack is its differentiator versus pure weight-loss telehealth — useful for patients already on testosterone or perimenopausal hormone protocols. Compounded semaglutide runs $99 the first month then $199/mo, and tirzepatide $149 then $299/mo, both billed quarterly.
Read our full Joi + Blokes review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Joi + Blokes
What we like
- Separate programs for women (Joi) and men (Blokes) — most GLP-1 telehealth is gender-agnostic
- Trustpilot 4.6/5 from 1,254+ reviews — among the strongest review signals in the category
- Monthly price includes medication, dosing support, clinician consults, and health coaching
- Integrated hormone + GLP-1 programs help patients on testosterone or perimenopausal protocols
- First-month discount ($99 sema / $149 tirz) lowers the barrier to trying GLP-1s
Watch-outs
- Billed quarterly — a 3-month commitment up front, not month-to-month
- Different pricing in NY and NJ — verify your state's cost before committing
- Per-state availability isn't listed; it's zip-code gated behind signup
- Months 2+ cost more ($199 sema / $299 tirz) than the headline intro price
- No FDA-approved Wegovy — compounded only on the GLP-1 side; Zepbound carries a separate visit fee
- No LegitScript or PCAB accreditation badge visible
Our Verdict
Joi + Blokes edges out 10rx with a higher overall score of 7.7/10 and is particularly strong for GLP-1 alongside men's and women's hormone-health programs. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Choose 10rx if…
You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.
Choose Joi + Blokes if…
You want GLP-1 alongside men's and women's hormone-health programs and a starting price around $99/mo.
Ready to start? Vetted GLP-1 providers
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Direct Meds
Listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →10rx vs Joi + Blokes: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.