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10rx vs Clume Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
Clume Health logo

Clume Health

7.1
★★★3.6/5

Best for: readers who want a separately priced microdose track and named dispensing pharmacies

Visit Clume Health

10rx and Clume Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $96.67/mo versus $219/mo, and both land at 7.1/10 overall. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$96.67/mo
semaglutide
Injectablecompounded injection
$149.67/mo
tirzepatide

Clume Health

Signature program, full dose — month-to-monthCompounded
$259/mo
semaglutide

The $186/mo figure is a 52-week prepaid term, not an ongoing monthly rate.

Signature program, full dose — month-to-monthCompounded
$259/mo
tirzepatide

The $186/mo figure is a 52-week prepaid term, not an ongoing monthly rate.

Microdose/Maintain program — month-to-monthCompounded
$219/mo
semaglutide

The $200/mo figure requires a 12-week prepaid term.

Microdose/Maintain program — month-to-monthCompounded
$219/mo
tirzepatide

The $200/mo figure requires a 12-week prepaid term.

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Clume Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Clume Health

7.1/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

7.0A
vs
B
6.5

Trust & Safety15%

5.3A
vs
B
7.5

Accessibility10%

7.5A
vs
B
7.0

Support10%

6.4A
vs
B
6.5

Features & Coverage

Feature10rxClume Health
Starting Price$96.67/mo$219/mo
Features8 features5 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Clume Health

Clume Health sells compounded semaglutide and tirzepatide in oral and injectable form across three tiers: a full-dose Signature program from $259/mo, a Microdose/Maintain program from $219/mo, and an NAD+ and sermorelin longevity track. Its terms name four dispensing pharmacies outright, which most compounded sellers will not do. Clinical care runs through OpenLoop, and cheaper per-month rates are available only by prepaying a 12- or 52-week term.

Read our full Clume Health review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Clume Health

What we like

  • Names four dispensing pharmacies in its terms, a level of disclosure most compounded sellers avoid.
  • Offers both full-dose and microdose tracks, so maintenance has its own priced program.
  • Sells semaglutide and tirzepatide in oral as well as injectable form.
  • Lists what the monthly price covers, including consultation, medication and at-home delivery.
  • Cancellation is allowed at any time by email or through the patient portal.

Watch-outs

  • The homepage advertises "starting at *$199/month" and "*$159/month", but no program is priced at either figure.
  • Those asterisks lead to no footnote anywhere on the page.
  • The cheapest advertised rates require prepaying a full term — $186/mo means a 52-week commitment.
  • Canceling needs 72 hours' notice before the next billing date or you are charged for that cycle.
  • No refund is issued for the month in which you cancel, or for any prior month.
  • Personalized options appear only after you accept OpenLoop's telehealth consent.
  • No LegitScript seal or other verified trust badge appears anywhere on the site.
  • Support is email only; no phone number or published hours.

Our Verdict

Both 10rx and Clume Health score equally well overall — the right choice depends on your priorities.

Choose 10rx if…

You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.

Choose Clume Health if…

You want readers who want a separately priced microdose track and named dispensing pharmacies and a starting price around $219/mo.

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6.9

TMates

Nationwide compounded GLP-1 availability including Puerto Rico

7.9

Trimi Health

Budget-conscious shoppers

7.4

Telos Rx

Needle-free, microdosed compounded GLP-1 with lab-monitored care

10rx vs Clume Health: FAQ

Key terms, explained

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