10rx vs Blue Sky MD
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Blue Sky MD
Best for: NC-based, LegitScript-certified; sema $40/wk or tirz $60/wk + coaching
Visit Blue Sky MD →10rx and Blue Sky MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $96.67/mo versus $160/mo, and 10rx edges ahead overall (7.1 vs 6.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Blue Sky MD
Verbatim: 'Semaglutide - $40/week in-office' and 'as low as $40/week'. Monthly estimate = $40 × 4 weeks = $160. Compounded formulation; dispensed in-office or shipped to home.
Verbatim: 'Tirzepatide - $60/week in-office'. Monthly estimate = $60 × 4 weeks = $240. Compounded formulation; dispensed in-office or shipped to home.
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 480+ providers' prices on their own sites and email you when tracked prices move.
What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Blue Sky MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Included
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Blue Sky MD
6.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Blue Sky MD |
|---|---|---|
| Starting Price | ✓$96.67/mo | $160/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 1 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Blue Sky MD
Blue Sky MD is a LegitScript-certified medical weight-loss practice founded in 2008 with seven North Carolina clinics and telehealth visits available. The program offers compounded semaglutide starting at $40/week and compounded tirzepatide starting at $60/week, dispensed directly to patients’ homes within 3–5 business days. Physician-supervised care includes 1-on-1 wellness coaching, a nutrition tracking app, hormone analysis, and personalized weight-loss plans. Medication access requires enrollment in their full medical weight-loss program.
Read our full Blue Sky MD review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Blue Sky MD
What we like
- LegitScript certified and physician-led since 2008; one of the most established GLP-1 practices in the Southeast
- Compounded semaglutide from $40/week (~$160/month) and tirzepatide from $60/week (~$240/month) — well below brand-name cost
- Comprehensive program includes 1-on-1 wellness coaching, nutrition plans, hormone analysis, and a proprietary mobile app
- Medication shipped directly to patients’ homes within 3–5 business days; telehealth visits available
- Insurance accepted in many cases; affordable self-pay options for uninsured patients
Watch-outs
- Geographic reach unclear — physical clinics in NC only; telehealth states beyond NC unconfirmed despite 'from virtually anywhere' claim
- Pricing quoted per-week ($40 sema / $60 tirz) rather than per-month; higher-dose pricing not disclosed
- Must enroll in full medical weight-loss program to access GLP-1 medications — medication-only Rx not offered
- No explicit lab testing protocol published; online FAQ does not confirm labs are included
- Small regional provider vs. national platforms; limited provider footprint outside North Carolina
Our Verdict
10rx edges out Blue Sky MD with a higher overall score of 7.1/10 and is particularly strong for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Blue Sky MD remains a solid alternative, especially if you're looking for NC-based, LegitScript-certified; sema $40/wk or tirz $60/wk + coaching.
Choose 10rx if…
You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.
Choose Blue Sky MD if…
You want NC-based, LegitScript-certified; sema $40/wk or tirz $60/wk + coaching and a starting price around $160/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
ShedRx
Mainstream telehealth GLP-1 access
From $149/mo
Get started →bmiMD
Mainstream telehealth GLP-1 access
From $99/mo
Get started →RNK Health
Compounded GLP-1 alongside NAD+, peptide and longevity add-ons
From $197/mo
Get started →10rx vs Blue Sky MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring 10rx and Blue Sky MD head-to-heads in the same category.
- 10rx vs Amazon One Medical
- 10rx vs Vytora Health
- 10rx vs Collective
- Blue Sky MD vs CoreAge Rx
- Blue Sky MD vs EverSlim
- Blue Sky MD vs Found
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.