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10rx vs Actin

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
Actin logo

Actin

7.0
★★★3.5/5

Best for: affordable compounded semaglutide with B12 enhancement

Visit Actin

10rx and Actin are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $96.67/mo versus $169/mo, and 10rx edges ahead overall (7.1 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$96.67/mo
semaglutide
Injectablecompounded injection
$149.67/mo
tirzepatide

Actin

Compounded GLP-1 (semaglutide + B12)Compounded
$169/mo
semaglutide

Month-to-month. Actin prints all three cadences on the product page: 1-Month $169, 3-Month $143, 6-Month $116, flat at every dose.

Compounded tirzepatide (with B12 or glycine) — month-to-monthCompounded
$269/mo
tirzepatide

ADDED 2026-08-15 — we had no tirzepatide row although Actin sells it. Ladder on the product page: 1-Month $269, 3-Month $209, 6-Month $166, flat at every dose.

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Actin

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Actin

7.0/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

7.0A
vs
B
7.0

Trust & Safety15%

5.3A
vs
B
7.3

Accessibility10%

7.5A
vs
B
7.0

Support10%

6.4A
vs
B
7.0

Features & Coverage

Feature10rxActin
Starting Price$96.67/mo$169/mo
Features8 features3 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Actin

Actin sells compounded semaglutide at $169/month and compounded tirzepatide at $269/month month-to-month, falling to $116 and $166 on a six-month plan, flat at every dose with no membership fee. It also offers a GLP-1 microdose at $149/month alongside longevity, sexual-wellness and hair treatments, and states plainly that it is not a compounding pharmacy itself.

Read our full Actin review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Actin

What we like

  • Semaglutide paired with B12 for added energy support
  • Transparent pricing — exact cost shown upfront with no hidden fees
  • Competitive pricing from $116/mo on the 6-month plan ($169/mo month-to-month)

Watch-outs

  • Semaglutide only — no tirzepatide or liraglutide
  • No visible LegitScript or PCAB accreditation
  • States served not disclosed
  • Broad platform spanning hormones, sexual wellness, and hair health

Our Verdict

Winner: 10rx

10rx edges out Actin with a higher overall score of 7.1/10 and is particularly strong for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.

Choose 10rx if…

You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.

Choose Actin if…

You want affordable compounded semaglutide with B12 enhancement and a starting price around $169/mo.

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10rx vs Actin: FAQ

10rx is cheaper. Its lowest ongoing monthly cash price is $96.67/mo, compared with $169/mo for Actin. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
10rx scores higher overall at 7.1/10 versus 7.0/10, and is particularly strong for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. That said, Actin is a better fit if you want affordable compounded semaglutide with B12 enhancement.
Neither 10rx nor Actin publicly lists its exact state availability. Most national GLP-1 telehealth providers operate in the majority of states — confirm your state is covered during sign-up.
Neither 10rx nor Actin is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, 10rx is cheaper at $96.67/mo versus $169/mo at Actin.

Key terms, explained

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Continue exploring 10rx and Actin head-to-heads in the same category.

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