Wegovy vs Compounded Semaglutide: Save up to $1,349/mo
In 2026, switching from brand Wegovy to compounded semaglutide can save the average patient about $16,188 per year — without changing the active ingredient.
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Cost Comparison
| Option | Monthly | Annual |
|---|---|---|
| Wegovy (brand cash price) | $1,349 | $16,188 |
| Compounded semaglutide (cheapest provider) | $0 | $0 |
| Your savings | $1,349 | $16,188 |
Why is Wegovy so expensive?
Wegovy is the FDA-approved brand-name formulation of semaglutide 2.4mg, made by Novo Nordisk for chronic weight management. While clinically effective, its $1,349/month list price makes it unaffordable for most cash-pay patients. Compounded semaglutide is a much more affordable alternative dispensed by licensed 503A pharmacies.
Compounded semaglutide is legal under Section 503A of the Federal Food, Drug, and Cosmetic Act, which allows licensed pharmacists to prepare customized medications for individual patients. Compounded semaglutide is not FDA-approved as a finished product, but the active ingredient is the same molecule used in Wegovy. The FDA has issued guidance on compounded GLP-1s, and patients should always verify their provider works with LegitScript-certified pharmacies.
Top Compounded Semaglutide Providers (2026)
24hrDOC
Best for: Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide
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AbundRX
Best for: Shoppers wanting straightforward two-tier compounded GLP-1 pricing with free shipping
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AM Rx
Best for: patients with insurance seeking brand-name GLP-1 access (review regulatory warnings carefully)
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AquaVita NextGen
Best for: patients in AZ/CA/FL/TX/NV seeking medspa-backed GLP-1 with a named medical director
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Ascend Vitality
Best for: Cash-pay compounded semaglutide & tirzepatide, injection or daily tablet
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Aspire Health
Best for: compounded + brand GLP-1s (Wegovy/Zepbound) with labs included and named PA/NP team in Nebraska telehealth
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Avono Health
Best for: shoppers who want a wide, transparently priced compounded GLP-1 menu including microdose and oral options
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AZ Health
Best for: Arizona-area shoppers wanting flat-rate compounded GLP-1 with no insurance and free shipping
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BetterMe Rx
Best for: patients who value pharmacy transparency — six named compounding partners
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BloomWell Rx
Best for: Budget-minded shoppers wanting transparent, low-cost compounded GLP-1 online
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Blue Sky MD
Best for: LegitScript-certified, NC-based; compounded sema $40/wk or tirz $60/wk; physician-led + 1-on-1 coaching
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Bodi Envi
Best for: Transparent flat-price compounded semaglutide & tirzepatide with no membership fee
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Bodybuilding Health+
Best for: fitness-brand compounded GLP-1 with hormone and performance programs
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Bon Health
Best for: shoppers wanting transparent, no-membership compounded GLP-1 with physician-titrated dosing
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boostAGErx
Best for: Cost-sensitive shoppers comfortable prepaying 12 months for low-cost compounded GLP-1
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Breeze Meds
Best for: compounded GLP-1 access with named prescribers and 4-pharmacy network
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Clinic Secret
Best for: Budget-focused patients wanting low-cost compounded GLP-1 with no membership fee
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CoraDoc
Best for: Shoppers wanting low flat-fee compounded GLP-1 nationwide with no subscription
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Curex
Best for: affordable compounded GLP-1 with strong corporate transparency and pharmacy testing
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Direct Meds
Best for: listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering
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DoctorAdam
Best for: adults seeking compounded oral or injectable GLP-1s with flat all-in monthly pricing
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Dr. Arevitalize
Best for: Compounded semaglutide & tirzepatide in both injection and oral-capsule forms
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Dr. Gillis' Wellness Center
Best for: Patients wanting sublingual ODT GLP-1 tablets or a needle-free weight-loss option
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DrBrainRx
Best for: Neurologist-founded compounded GLP-1 with LegitScript certification and flat-rate pricing
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DrMedHealth
Best for: Cost-conscious patients seeking low-priced compounded GLP-1s from a LegitScript-certified clinic.
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DudeMeds
Best for: men seeking no-fee GLP-1 access with oral and injectable options
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Elara Health and Wellness
Best for: bundled-care GLP-1 with labs and coaching from four named pharmacies
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Elevate Health
Best for: Shoppers who want compounded or brand-name tirzepatide with payment plans and add-on therapies
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ElitePhysiqMD
Best for: adults wanting compounded GLP-1 from $145/mo with peptide therapy options and HSA/FSA eligibility
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ElixaMD
Best for: Shoppers wanting low-cost compounded semaglutide with free dietician and coaching included
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Eloria
Best for: No-membership compounded GLP-1 from $179, with a brand Wegovy option and board-certified online care
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Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
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EverFit Medical
Best for: hybrid Ohio clinic care with body-composition and red-light adjuncts
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Fidelity Medical Clinic
Best for: Low-cost compounded semaglutide & tirzepatide from a clinic-plus-telehealth hybrid
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Fifty 410
Best for: Budget-focused buyers wanting transparent no-membership compounded GLP-1 pricing
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FitFlow
Best for: Annual-prepay shoppers wanting the lowest compounded GLP-1 price with board-certified telehealth care
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Fitness RX
Best for: Shoppers wanting an all-in, low monthly GLP-1 plan bundled with fitness coaching
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Fresh Day Meds
Best for: lowest-cost compounded GLP-1 from a LegitScript-certified Texas platform
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Gala
Best for: compounded GLP-1/GIP combo therapy on a yearly subscription with free shipping nationwide
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Garcia Weight Loss, Aesthetics & Hormone Therapy
Best for: Florida residents who want an established in-person weight-loss clinic with provider-supervised GLP-1 care
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Gaya Wellness
Best for: Women 40+ wanting GLP-1 weight loss integrated with menopause and hormone care
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Genesis Health
Best for: adults seeking compounded or brand GLP-1s with coaching and annual pricing from $99/mo
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Get Thin MD
Best for: lowest-priced compounded semaglutide on a 3-month commitment, with brand-name Ozempic/Zepbound also available
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GetRelief Rx
Best for: sublingual (non-injectable) compounded GLP-1 drops for the needle-averse
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Gimme Care
Best for: affordable compounded GLP-1 with nationwide coverage and microdose options
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Go Vida Plena
Best for: Spanish-speaking patients wanting a bilingual, Latino-food-friendly GLP-1 program from $199/mo
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Good Girl Rx
Best for: patients seeking multiple compounded GLP-1 formats with pharmacy quality standards
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Harbor
Best for: adults seeking the lowest-cost compounded GLP-1 with physician oversight and a 12-month money-back guarantee
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Harmony Wellness Clinic
Best for: Compounded semaglutide and tirzepatide from LegitScript-certified telehealth in 36 states
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He & She MD
Best for: Transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name access
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Heally
Best for: Patients wanting a wide GLP-1 menu (branded or compounded) from a LegitScript-verified platform.
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Healthicare
Best for: buyers who want a transparent, named-clinician + named-pharmacy compounded GLP-1 option in 44 states
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HealthSource
Best for: compounded semaglutide or tirzepatide (injection or oral) in all 50 states from $199/mo
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Helios Meds
Best for: Transparent low-cost compounded semaglutide from a LegitScript-approved telehealth provider
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Heros Health
Best for: Compounded semaglutide & tirzepatide with a 90-day money-back guarantee
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HumeCare+
Best for: People who want GLP-1 weight loss with real-time body-composition tracking to protect muscle
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Immortals
Best for: Bryan Johnson's longevity telehealth: compounded sema/tirz microdose injections from $167/mo
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Invigor Medical
Best for: patients wanting an established multi-service clinic over a GLP-1-only specialist
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iThriveMD
Best for: Shoppers wanting compounded GLP-1 within a lab-driven longevity and hormone clinic
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Jently
Best for: Shoppers wanting transparent compounded GLP-1 pricing plus NAD+, peptides, and metformin in one place
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Jyra Health
Best for: Budget shoppers wanting very low-cost compounded semaglutide or tirzepatide in any state
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Kina
Best for: Women in menopause wanting GLP-1 weight care alongside HRT, from board-certified physicians
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Kongo
Best for: Low-cost compounded semaglutide or tirzepatide nationwide with no membership and everything included
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LeanDose
Best for: Doctor-supervised compounded semaglutide or tirzepatide with transparent all-inclusive pricing
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LevelUp Rx
Best for: compounded semaglutide and tirzepatide at a flat price with named pharmacies
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LifeRx.md
Best for: Budget patients wanting flat, dose-independent compounded GLP-1 pricing nationwide.
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Liv Body
Best for: compounded GLP-1 paired with a muscle-preservation supplement stack
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LIV by WellNow
Best for: Patients in IL, IN, MI, NY, or PA wanting flat all-inclusive compounded semaglutide
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Live Vital
Best for: shoppers who want low-cost, physician-led compounded GLP-1 with peptide and hormone options
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Livea
Best for: Comprehensive physician-supervised GLP-1; compounded sema $99/mo; 8 clinics + telehealth, MN/WI/IA/FL only
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Luci
Best for: Budget shoppers wanting low-cost compounded semaglutide or tirzepatide, including oral pill options
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Luma Meds
Best for: people who want a LegitScript-certified compounded GLP-1 plan with free shipping and provider support
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Lumora
Best for: adults wanting physician-led compounded GLP-1 care with labs, follow-up, and peptide options included
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MANÜ Telehealth
Best for: Cash-pay shoppers wanting low daily-cost compounded GLP-1 with simple online onboarding
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Maves (Homera Health)
Best for: $99 first-month semaglutide with men's-health and body-optimization framing
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Maximus
Best for: men seeking compounded GLP-1 alongside testosterone optimization
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Measured
Best for: people who want coaching-forward metabolic care and the choice of compounded or brand-name GLP-1s
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MedLeanRx
Best for: Texas patients wanting physician-guided access to brand or compounded GLP-1
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Medsol RX
Best for: shoppers who want flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach
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MEDVi
Best for: patients who want the option to switch between compounded and brand-name GLP-1 through one provider
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MyFastRx
Best for: Cash-pay patients comfortable with 12-month upfront billing for the lowest compounded-GLP-1 monthly rate.
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MyStart Health
Best for: fastest compounded GLP-1 onboarding with a price lock
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NexLife
Best for: pharmacy-quality-conscious patients seeking LegitScript + NABP-certified compounded GLP-1
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Next Vial
Best for: people seeking compounded GLP-1 care with LegitScript certification and a named pharmacy partner
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NiceRx
Best for: patients seeking batch-tested compounded GLP-1 with transparent entity disclosure
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NuDay Rx
Best for: Shoppers wanting both compounded and brand GLP-1 options with coaching and a doctor consult
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Ondra Health
Best for: Cost-sensitive patients who want the lowest compounded-GLP-1 monthly cost and are willing to commit quarterly.
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Onyx Weight Loss
Best for: NP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl.
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Optimized Health
Best for: Patients in MO/IA/KS/UT/WA wanting transparent, lab-guided compounded GLP-1 weight loss
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OurView Health
Best for: Budget shoppers wanting low-cost compounded GLP-1 via a membership savings model
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PeterMD
Best for: men seeking flat-priced compounded GLP-1 access alongside TRT or peptide therapy
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PlexusDx
Best for: Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization
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Potere Health MD
Best for: Utah residents wanting low-cost, physician-led GLP-1 weight loss without a subscription
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Precision Telemed
Best for: transparent month-to-month compounded GLP-1 with pharmacy quality documentation
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Premium Health
Best for: Buyers wanting an all-inclusive compounded GLP-1 membership with named pharmacies
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Primary Clinic (Direct GLP)
Best for: GLP-1 at wholesale cost inside a Direct Primary Care membership
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Prime Health
Best for: Shoppers wanting LegitScript-certified compounded GLP-1 at a flat, dose-independent monthly price
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Red Mountain Weight Loss
Best for: hybrid clinic-plus-telehealth GLP-1 from a 30-year obesity-medicine specialist
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Rejuve Meds
Best for: Shoppers wanting transparent, low-cost compounded GLP-1 with no membership fees and HSA/FSA eligibility
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REMEVi
Best for: Spanish-speaking patients wanting bilingual, LegitScript-certified compounded GLP-1
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RestorLife Med
Best for: GLP-1 weight care from a named board-certified physician, with microdosing and strong clinical support
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RNK Health
Best for: compounded GLP-1 alongside NAD+, peptide and longevity add-ons
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Roen Rx
Best for: patients with insurance seeking brand-name GLP-1 access with compounded fallback
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RxPepsDirect
Best for: Lowest per-vial GLP-1 cost: compounded sema $25, tirz $45, $39 telehealth Rx, no subscription, 28 states
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RxSaludable
Best for: Spanish-speaking patients who want compounded GLP-1 care from Spanish-speaking providers
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RxSpan MD
Best for: shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
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Semaglutide Online
Best for: LegitScript GLP-1 nationwide ex. AL; compounded sema $199 or tirz $299/mo all-in; financing from $79/mo
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Shapely
Best for: Insurance-accepted telehealth with compounded sema $99/mo and tirz $166/mo; CA, FL, NY, TX (expanding)
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Signos
Best for: Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app
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Silhouette MD
Best for: people who want hands-on concierge support alongside compounded GLP-1 treatment
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Somi Health
Best for: low-cost compounded semaglutide or tirzepatide, plus an oral no-needle option
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Somira Health
Best for: Simple, flat-priced compounded semaglutide or tirzepatide with free overnight shipping
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Southern Vitality and Weight Loss
Best for: Cost-sensitive shoppers wanting cheap compounded GLP-1 from a provider that names its pharmacies
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Sprout Health
Best for: LegitScript-verified compounded GLP-1 via named pharmacies
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Sunlight
Best for: compounded GLP-1 with unlimited telehealth visits and free shipping
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SynergenX Health
Best for: TX patients wanting clinic-backed GLP-1 telehealth; compounded sema from $150/mo, med+ship incl.
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TeleCareSpot
Best for: Flat-priced, LegitScript-verified compounded semaglutide or tirzepatide with broad state coverage
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TeleDocs360
Best for: Cash-pay patients wanting compounded GLP-1 options with transparent base pricing
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TelePeptide
Best for: All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states
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Telos Rx
Best for: Needle-free and microdosed compounded GLP-1 options with lab-monitored care
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TMates
Best for: nationwide compounded GLP-1 availability including Puerto Rico
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TOM Weight Loss
Best for: Texas or Utah patients wanting direct ABOM-certified physician access at competitive flat-rate pricing
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Trava Health
Best for: Cash-sensitive patients comfortable with multi-pharmacy 503A sourcing without LegitScript verification
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Trillium Meds
Best for: LegitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo)
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Try Ageless
Best for: lowest-tier compounded GLP-1 in injection, troche and sublingual forms
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TRYM Health
Best for: Budget-focused shoppers wanting low-cost compounded GLP-1 vials shipped nationwide
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Tyde Wellness
Best for: compounded GLP-1 with five named LegitScript-certified pharmacy partners
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Valhalla Vitality
Best for: Patients wanting compounded GLP-1 plus peptide and hormone therapies on one platform
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VirtualCare2Go
Best for: Same-day compounded semaglutide (injection or oral tablet) with nationwide shipping
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Vital Edge
Best for: people who want transparent flat-fee GLP-1 pricing with oral and brand-name options
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VyrarX
Best for: compounded semaglutide ($179/mo) and tirzepatide ($329/mo) via LegitScript-certified telehealth in 47 states
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Vytora Health
Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states
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WeightCare
Best for: patients prioritizing pharmacy quality standards (PCAB) with coaching support
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Whoosh Wellness
Best for: shoppers wanting all-inclusive compounded GLP-1 alongside a peptide/recovery stack
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Woodwork
Best for: Low-cost compounded GLP-1 (oral or injectable) on an LGBTQ-focused men's health platform
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YourHealthRx
Best for: Science-forward GLP-1 and peptide care nationwide, with flat-rate dosing and built-in clinical follow-up
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Zealthy
Best for: not currently recommended — listed for transparency and reader awareness only
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Zera Health
Best for: budget GLP-1 shoppers who want flat all-dose pricing and a named 503A pharmacy
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ZYP Medical
Best for: Men in NE, IA, SD, KS, CO, or AZ wanting low-cost compounded GLP-1s with oral option
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Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Wegovy · Drugs and brands
- Ozempic · Drugs and brands
- Zepbound · Drugs and brands
- Mounjaro · Drugs and brands
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
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