Youth & Soul vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Youth & Soul
Best for: shoppers who want many treatment categories in one account and are willing to verify claims themselves
Visit Youth & Soul →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Youth & Soul and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $149/mo, and NewSelf edges ahead overall (8.3 vs 5.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Youth & Soul
Compounded semaglutide 0.25mg to 1mg titration with a B12 injection, physician consultation and shipping included.
Higher-dose semaglutide 1mg to 2.4mg with metformin 500mg and a B12 plus Lipo-C injection.
Compounded tirzepatide 2.5mg to 15mg with metformin XR, B12 plus MIC and an NAD+ nasal spray.
NewSelf
All dosages same price
All dosages same price
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What’s included
Youth & Soul
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Youth & Soul
5.8/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Youth & Soul | NewSelf |
|---|---|---|
| Starting Price | $149/mo | ✓$100/mo |
| Features | 4 features | ✓6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Youth & Soul
Ten-vertical telehealth marketplace selling compounded GLP-1 tiers alongside HRT, ED, nootropics and peptides, running on the Bask Health platform.
Read our full Youth & Soul review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Youth & Soul
What we like
- Three GLP-1 tiers priced openly, with the dose range and every included component listed per tier
- Full refund advertised if you are not approved
- Physician consultation, prescription and shipping stated as included in the plan price
- Ten treatment verticals under one account, from GLP-1 to HRT, peptides and mental health
Watch-outs
- Describes its compounded medications as FDA-Approved Compounds, which is false: compounded drugs are not FDA-approved
- Presents scraped third-party comments as testimonials, several using Reddit usernames and some describing brand Wegovy or Mounjaro
- Its own copy promises never to fabricate testimonials while displaying those scraped comments
- Homepage trust counters render as 0K+ medical professionals, 0.0M+ patients and 0M+ successful orders
- Labels its compounded tirzepatide a Mounjaro compound, conflating a compounded drug with the brand
- Uses artificial scarcity: Currently 3 Telemed Doctor Consultations Available Today
- No state list, no named pharmacy and no named legal entity anywhere on the site
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Youth & Soul with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Youth & Soul remains a solid alternative, especially if you're looking for shoppers who want many treatment categories in one account and are willing to verify claims themselves.
Choose Youth & Soul if…
You want shoppers who want many treatment categories in one account and are willing to verify claims themselves and a starting price around $149/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Ready to start? Vetted GLP-1 providers
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YourEra
$99 first-month entry pricing on compounded GLP-1s
From $99/mo
Get started →Gala
Compounded GLP-1/GIP combo therapy on a yearly subscription with free shipping nationwide
From $129/mo
Get started →TMates
Nationwide compounded GLP-1 availability including Puerto Rico
From $249/mo
Get started →Youth & Soul vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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