YourHealthRx vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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YourHealthRx
Best for: Science-forward GLP-1 and peptide care, flat-rate dosing, built-in follow-up
Visit YourHealthRx →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →YourHealthRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $170/mo, and NewSelf edges ahead overall (8.3 vs 7.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
YourHealthRx
Weekly injectable + B12; $140 first month and on a 6-month plan. Oral dissolving tablet $180/mo. Flat price regardless of dose.
Weekly injectable + B12; $190 first month and on a 6-month plan. Oral dissolving tablet $220/mo. Flat price regardless of dose.
NewSelf
All dosages same price
All dosages same price
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What’s included
YourHealthRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
YourHealthRx
7.9/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | YourHealthRx | NewSelf |
|---|---|---|
| Starting Price | $170/mo | ✓$100/mo |
| Features | ✓8 features | 6 features |
| States Available | ✓51 | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | ✓None | 1 warning |
About YourHealthRx
YourHealthRx is a scientist-founded peptide and GLP-1 telehealth platform available in all 50 states and DC via a multi-state (IMLC) clinician network. Compounded semaglutide and tirzepatide come as a weekly injectable (with B12) or a daily oral tablet, at a flat subscription price that doesn't change with your dose - injectable semaglutide ~$170/mo and tirzepatide ~$210/mo ongoing. It also offers a broad peptide catalog plus lab testing. Prescribing runs through partner clinical workflows; compounded meds aren't FDA-approved, the pharmacy isn't named, and no LegitScript is shown.
Read our full YourHealthRx review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
YourHealthRx
What we like
- Available in all 50 states and DC through a multi-state (IMLC) licensed clinician network
- Compounded semaglutide and tirzepatide in two formats - weekly injectable (with B12) or daily oral dissolving tablet
- Flat subscription price that doesn't change as your dose increases (no titration penalty)
- Science-forward, clinician-led, with built-in follow-up, lab testing, and a broad peptide and longevity catalog (BPC-157, TB-500, sermorelin, NAD+)
- Transparent, education-first positioning with published medical disclaimer, privacy, and terms
Watch-outs
- Eligibility and prescribing run through partner clinical workflows - YourHealthRx is the platform, not the prescriber or pharmacy
- Compounded medications are not FDA-approved - not brand Wegovy, Ozempic, Zepbound, or Mounjaro
- The compounding pharmacy partner is not named ('transparent sourcing' claimed but no pharmacy disclosed)
- Headline prices include a first-month intro rate; ongoing monthly cost is higher (semaglutide ~$170, tirzepatide ~$210)
- No LegitScript certification displayed
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out YourHealthRx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. YourHealthRx remains a solid alternative, especially if you're looking for Science-forward GLP-1 and peptide care, flat-rate dosing, built-in follow-up.
Choose YourHealthRx if…
You want Science-forward GLP-1 and peptide care, flat-rate dosing, built-in follow-up and a starting price around $170/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Try Ageless
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Compounded GLP-1 with unlimited telehealth visits and free shipping
From $159/mo
Get started →MadeMed
Compounded GLP-1 in both injection and oral forms
From $219/mo
Get started →YourHealthRx vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.