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Vital Harmony Rx vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Vital Harmony Rx logo

Vital Harmony Rx

6.0
★★★☆☆3/5

Best for: LegitScript-verified compounded GLP-1 with semaglutide and tirzepatide options

Visit Vital Harmony Rx
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Vital Harmony Rx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts at $100/mo, and NewSelf edges ahead overall (8.3 vs 6.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Vital Harmony Rx

Pricing not publicly listed.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Vital Harmony Rx

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Vital Harmony Rx

6.0/10

Overall

NewSelf

8.3/10

Value25%

5.0A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

6.0A
vs
B
8.0

Trust & Safety15%

6.0A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

5.4A
vs
B
7.9

Features & Coverage

FeatureVital Harmony RxNewSelf
Starting Price$100/mo
Features4 features6 features
States AvailableNot disclosed49
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Vital Harmony Rx

Vital Harmony Rx is a telehealth platform offering compounded injectable GLP-1 therapy — semaglutide (GLP-1 + B12) and tirzepatide (GLP-1/GIP + B12) — plus a wellness-peptide menu of NAD+, sermorelin, and glutathione. Care runs through an independent physician network (Beluga Health), and the site carries a verified LegitScript seal. Services are offered nationwide; note that no pricing is published on the site, so cost can't be compared in advance.

Read our full Vital Harmony Rx review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Vital Harmony Rx

What we like

  • Verified LegitScript certification (ID 49230211) — a trust signal many compounded-GLP-1 DTC brands lack
  • Explicit compounded-medication + 'not a pharmacy/manufacturer' disclosure on-site
  • Both a semaglutide (GLP-1+B12) and a tirzepatide (GLP-1/GIP+B12) option
  • Operates on a named physician network (Beluga Health)

Watch-outs

  • NO pricing published anywhere on the site — a major gap for a cost-comparison directory; buyers cannot evaluate value without contacting the company
  • No specific state list (only 'entire country' claimed)
  • No named compounding pharmacy partner
  • No named medical director / PIC, no legal entity or governing law disclosed
  • Molecule strengths/dose tiers not published

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Vital Harmony Rx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Vital Harmony Rx remains a solid alternative, especially if you're looking for LegitScript-verified compounded GLP-1 with semaglutide and tirzepatide options.

Choose Vital Harmony Rx if…

You want LegitScript-verified compounded GLP-1 with semaglutide and tirzepatide options.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Vital Harmony Rx vs NewSelf: FAQ

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