Vital Edge vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Vital Edge
Best for: transparent flat-fee GLP-1 pricing with oral and brand-name options
Visit Vital Edge →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Vital Edge and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Vital Edge
Compounded oral capsules
Compounded oral capsules
Weekly subcutaneous injection
Weekly subcutaneous injection
Brand-name oral semaglutide
NewSelf
All dosages same price
All dosages same price
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 500+ providers' prices on their own sites and email you when tracked prices move.
What’s included
Vital Edge
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Vital Edge
7.1/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Vital Edge | NewSelf |
|---|---|---|
| Starting Price | $199/mo | ✓$100/mo |
| Features | ✓7 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | ✓None | 1 warning |
About Vital Edge
Vital Edge is a Chattanooga, TN telehealth practice offering physician-supervised GLP-1 weight loss nationwide by video, with medication shipped to your door each month. It carries an unusually broad menu — compounded semaglutide ($350/mo) and tirzepatide ($450/mo), compounded oral capsules from $199/mo, and brand-name Ozempic, Wegovy, Mounjaro and Rybelsus — all at a flat monthly fee that includes the consult, medication and shipping with no dosage upcharge.
Read our full Vital Edge review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Vital Edge
What we like
- Transparent flat monthly pricing published on-site — consult, medication, and shipping all included
- Broad menu: compounded semaglutide/tirzepatide, compounded oral capsules from $199/mo, plus brand-name Ozempic, Wegovy, Mounjaro and Rybelsus
- LegitScript-certified (seal #43281221)
- Flat fee with no upcharge as your dose increases
- Compounded oral GLP-1 capsules available for needle-free dosing
Watch-outs
- Compounded injectable pricing ($350 semaglutide / $450 tirzepatide) runs above the lowest-cost telehealth options
- No compounding pharmacy partner named on the site
- No named medical director or prescribing clinicians
- State availability not published — only a nationwide virtual-care claim
- Small, locally-rooted operation with a limited public track record
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Vital Edge with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Vital Edge remains a solid alternative, especially if you're looking for transparent flat-fee GLP-1 pricing with oral and brand-name options.
Choose Vital Edge if…
You want transparent flat-fee GLP-1 pricing with oral and brand-name options and a starting price around $199/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Gala
Compounded GLP-1/GIP combo on a yearly plan with free shipping
From $149/mo
Get started →TMates
Nationwide compounded GLP-1 availability including Puerto Rico
From $249/mo
Get started →RNK Health
Compounded GLP-1 alongside NAD+, peptide and longevity add-ons
From $197/mo
Get started →Vital Edge vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Vital Edge and NewSelf head-to-heads in the same category.
- Vital Edge vs Amazon One Medical
- Vital Edge vs Vytora Health
- Vital Edge vs Collective
- NewSelf vs CoreAge Rx
- NewSelf vs EverSlim
- NewSelf vs Found
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.