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Trellis Vitality vs CoreAge Rx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Trellis Vitality logo

Trellis Vitality

7.5
★★★3.8/5

Best for: body-composition tracking and flat per-dose pricing without a membership fee

Visit Trellis Vitality
VS
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx

Trellis Vitality and CoreAge Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $99/mo versus $150/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Trellis Vitality

Month-to-month, all dosages same priceCompounded
$150/mo
semaglutide

Per-month rate falls on longer plans: $150 monthly, $140 on 3 months, $133 on 6 months. All dosages cost the same.

Month-to-month, all dosages same priceCompounded
$199/mo
tirzepatide

Per-month rate falls on longer plans: $199 monthly, $189 on 3 months, $179 on 6 months. All dosages cost the same.

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

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What’s included

Trellis Vitality

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Trellis Vitality

7.5/10

Overall

CoreAge Rx

8.3/10

Value25%

8.0A
vs
B
8.5

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

7.5A
vs
B
8.5

Trust & Safety15%

6.5A
vs
B
7.8

Accessibility10%

8.0A
vs
B
8.0

Support10%

7.0A
vs
B
8.4

Features & Coverage

FeatureTrellis VitalityCoreAge Rx
Starting Price$150/mo$99/mo
Features7 features6 features
States Available5050
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About Trellis Vitality

Trellis Vitality is an online longevity clinic that frames weight loss around body composition rather than scale weight. Compounded semaglutide starts at $150 a month and tirzepatide at $199, with every dose priced the same and no membership or consult fee layered on top. The programme pairs GLP-1s with at-home biomarker panels, a 90-day re-test, and muscle-preserving options such as tesamorelin and glycine formulations. Trellis is a care-coordination company; prescribing is done by the Arora Health provider network and dispensing by Houston pharmacy VialsRX.

Read our full Trellis Vitality review →

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

Pros & Cons

Trellis Vitality

What we like

  • Names both its pharmacy (VialsRX, Houston TX) and its prescribing network, with a street address and phone number for the pharmacy.
  • All dosages cost the same, and there is no membership fee or consult charge on top of the monthly price.
  • Frames the programme around body composition, with at-home biomarker panels and a 90-day re-test rather than scale weight alone.
  • Will review labs from an existing compounded programme and recommend protocol adjustments free of charge.

Watch-outs

  • Headline stats (92% biomarker improvement, $4,000 average annual saving, 3.4 weeks saved) are unsourced and cannot be checked.
  • The "4.7 / 5 · 5,000+ current patients" rating names no review platform, so it cannot be verified against a public record.
  • Prescribing runs through the Arora Health network, which several unrelated telehealth brands also use, so the clinical layer is not exclusive.
  • Refund eligibility is decided per order rather than by a stated policy, so outcomes are discretionary.

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out Trellis Vitality with a higher overall score of 8.3/10 and is particularly strong for best overall value. Trellis Vitality remains a solid alternative, especially if you're looking for body-composition tracking and flat per-dose pricing without a membership fee.

Choose Trellis Vitality if…

You want body-composition tracking and flat per-dose pricing without a membership fee and a starting price around $150/mo.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

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Trellis Vitality vs CoreAge Rx: FAQ

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