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TeleClinic vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
TeleClinic logo

TeleClinic

7.3
★★★3.7/5

Best for: Transparent, cash-pay compounded GLP-1 from a named 503A pharmacy across 47 states

Visit TeleClinic
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical

TeleClinic and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $199/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

TeleClinic

MonthlyCompounded
$199/mo
semaglutide

Ongoing month-to-month; first-quarter intro $139/mo billed quarterly

MonthlyCompounded
$299/mo
tirzepatide

Ongoing month-to-month; first-quarter intro $219/mo billed quarterly

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

TeleClinic

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

TeleClinic

7.3/10

Overall

Amazon One Medical

8.5/10

Value25%

7.0A
vs
B
8.5

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
8.8

Accessibility10%

7.5A
vs
B
9.5

Support10%

7.0A
vs
B
8.0

Features & Coverage

FeatureTeleClinicAmazon One Medical
Starting Price$199/mo$149/mo
Features6 features6 features
States Available4750
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About TeleClinic

TeleClinic (Teleclinic Holdings LLC) is a US telehealth platform offering physician-prescribed compounded GLP-1 weight-loss medication — semaglutide and tirzepatide — shipped from a licensed 503A compounding pharmacy. Programs are cash-pay with no insurance, flat monthly pricing, and free shipping across 47 states. Prescriptions are filled by Rush Pharmacy, a 503A compounder TeleClinic describes as PCAB-accredited. It also offers NAD+ and B12/MIC injections. TeleClinic is LegitScript certified; compounded semaglutide and tirzepatide are not FDA-approved.

Read our full TeleClinic review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

TeleClinic

What we like

  • Names its pharmacy partner — Rush Pharmacy, a licensed 503A compounder — which many compounded-GLP-1 telehealths won't disclose
  • LegitScript certified with flat, published monthly pricing, free shipping, and no insurance required
  • Broad access: 47 states with US-licensed physicians and transparent cash-pay pricing

Watch-outs

  • Compounded semaglutide and tirzepatide only — no brand-name GLP-1 (Wegovy or Zepbound) option
  • Headline $139/$219 rates are first-quarter intro prices billed quarterly; ongoing month-to-month is $199/$299
  • Not available in California, South Carolina, or New Jersey

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out TeleClinic with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. TeleClinic remains a solid alternative, especially if you're looking for Transparent, cash-pay compounded GLP-1 from a named 503A pharmacy across 47 states.

Choose TeleClinic if…

You want Transparent, cash-pay compounded GLP-1 from a named 503A pharmacy across 47 states and a starting price around $199/mo.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

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TeleClinic vs Amazon One Medical: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.