Superpower vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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Superpower
Best for: Members who want lab testing bundled with a GLP-1 prescription, not just medication
Visit Superpower →
Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →Superpower and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $199/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Superpower
Marketing 'from' price on superpower.com/semaglutide; the standalone Marketplace product listing for the same compounded semaglutide shows $229/mo. Separate from the $199/year membership fee.
Brand Ozempic 'from' price shown alongside the compounded option on the same page; same bimonthly upfront-billing cadence applies.
Amazon One Medical
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What’s included
Superpower
What the monthly price covers
Medication
Included
Provider visits
Not disclosed
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Superpower
7.1/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Superpower | Amazon One Medical |
|---|---|---|
| Starting Price | $199/mo | ✓$149/mo |
| Features | ✓7 features | 6 features |
| States Available | 42 | ✓50 |
| Compounded | ✓ Yes | — |
| Brand Name | ✓ Yes | ✓ Yes |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About Superpower
Superpower is a $199-per-year health membership built around twice-yearly 100+ biomarker lab testing, not a single-purpose GLP-1 shop. Members who are clinically appropriate can add prescription treatments -- including compounded semaglutide or brand-name Ozempic -- through Superpower's in-house Marketplace, billed separately from the membership fee. Pharmacy fulfillment runs through named partners Strive Pharmacy, Belmar Pharmacy, and Progress Pharmacy.
Read our full Superpower review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
Superpower
What we like
- Twice-yearly 100+ biomarker lab testing bundled into every membership, not just a GLP-1 prescription mill
- Named compounding pharmacy partners: Strive Pharmacy, Belmar Pharmacy, and Progress Pharmacy
- 30-day money-back guarantee on the GLP-1 medication itself if it isn't a fit
- Real, claimed Trustpilot profile: 4.6/5 from 309 reviews
- Both compounded semaglutide and brand-name Ozempic offered on one page
- Available in 42 of 51 US jurisdictions (50 states + DC) per its own published list
- 24/7 care team access claimed, plus a published members@superpower.com support contact
Watch-outs
- Two separate $199 charges with different meanings ($199/year membership vs. 'from $199/month' medication) risk confusing shoppers
- GLP-1 'from $199/month' is billed every 2 months, paid upfront in full -- not a true monthly charge
- Marketplace list price for the same compounded semaglutide is $229/mo, above the landing-page 'from' figure
- $199/year membership fee is non-refundable even though the medication carries a 30-day guarantee
- LegitScript certification is only a text claim on-site; no verifiable seal or badge image was found
- No health insurance accepted
- Mandatory binding arbitration and class-action waiver in the Terms of Service
- Not available in Alaska, Arkansas, Hawaii, Louisiana, Mississippi, North Dakota, Rhode Island, South Dakota, or Wyoming
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out Superpower with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Superpower remains a solid alternative, especially if you're looking for Members who want lab testing bundled with a GLP-1 prescription, not just medication.
Choose Superpower if…
You want Members who want lab testing bundled with a GLP-1 prescription, not just medication and a starting price around $199/mo.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
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Sesame Care
Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $159/mo
Get started →Superpower vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.