Somi Health vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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Somi Health
Best for: low-cost compounded semaglutide or tirzepatide, plus an oral no-needle option
Visit Somi Health →
Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →Somi Health and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Somi Health starts lower at $135/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Somi Health
$135/mo on the 3-month plan, 'ANY DOSE.' Verified joinsomi.com 2026-06-19.
$165/mo on the 3-month plan, 'ANY DOSE.' Verified joinsomi.com 2026-06-19.
Semaglutide Tablet (no shots), $279/mo on the 1-month plan. Verified joinsomi.com 2026-06-19.
Amazon One Medical
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What’s included
Somi Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Somi Health
7.7/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Somi Health | Amazon One Medical |
|---|---|---|
| Starting Price | ✓$135/mo | $149/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Somi Health
Somi Health is a telehealth weight-loss provider offering compounded GLP-1 medications - compounded semaglutide and tirzepatide injections plus an oral semaglutide tablet. A US-licensed clinician reviews a short online intake, and one transparent monthly price covers the medical visit, ongoing medication shipments and direct provider messaging. Compounded semaglutide starts at $135/mo and tirzepatide at $165/mo on the 3-month plan, one price at any dose.
Read our full Somi Health review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
Somi Health
What we like
- Among the lowest compounded prices: semaglutide $135/mo, tirzepatide $165/mo (3-month plan)
- Oral semaglutide tablet option for those who want no injections
- One price at any dose, with the medical visit and shipping included
- LegitScript Approved seal displayed; partnered with 503A pharmacies
- Free 2-5 day shipping; no insurance required
Watch-outs
- Compounded only - no brand-name Wegovy, Zepbound, Ozempic or Mounjaro
- Homepage advertises a 100% money-back guarantee but Terms state all sales are final, no refunds on medication
- Partner pharmacies are not individually named (material transparency gap)
- No single prescribing medical group named; only affiliated professional entities
- State availability not published; confirmed only during intake
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out Somi Health with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Somi Health remains a solid alternative, especially if you're looking for low-cost compounded semaglutide or tirzepatide, plus an oral no-needle option.
Choose Somi Health if…
You want low-cost compounded semaglutide or tirzepatide, plus an oral no-needle option and a starting price around $135/mo.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Ready to start? Vetted GLP-1 providers
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TrimRx
Best overall value
From $135/mo
Get started →Sprout Health
LegitScript-verified compounded GLP-1 via named pharmacies
From $149/mo
Get started →PeterMD
Men seeking flat-priced compounded GLP-1 access alongside TRT or peptide therapy
From $105/mo
Get started →Somi Health vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.