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SkinnyRx vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
SkinnyRx logo

SkinnyRx

7.6
★★★3.8/5

Best for: mainstream telehealth GLP-1 access

Visit SkinnyRx
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

SkinnyRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $149.25/mo, and SkinnyRx is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

SkinnyRx

As low asCompounded
$149.25/mo
semaglutide

'As low as $149.25/mo*' — plan-length/promo dependent (matches the sitewide '25% lower prices' promo, $199 x 0.75); standard single-month rate not published pre-intake. Microdose available; free overnight shipping.

As low asCompounded · oral
$199/mo
semaglutide

'As low as $199/mo*' on /products/semaglutide-oral; once-daily.

As low asCompounded
$249/mo
semaglutide

'As low as $249/mo*' on /products/semaglutide-tablets.

As low asCompounded
$224.25/mo
tirzepatide

'As low as $224.25/mo*' and 'Starting at $224.25/mo with free overnight shipping'; microdose available; once-weekly.

As low asCompounded
$224.25/mo
tirzepatide

'As low as $224.25/mo*' on /products/tirzepatide-tablets; once-daily.

Monthly planCompounded
$1400/mo
semaglutide

'$1,400/mo*' — '*Price shown applies to Monthly plan paid upfront or with buy now, pay later programs.' 'No membership fees. Same price at every dose.'

Monthly planCompounded
$1400/mo
semaglutide

'$1,400/mo*' on /products/wegovy-injectable. Wegovy PILL is listed 'Unavailable' ('available via SkinnyRx Membership', fee not published).

Monthly planCompounded
$1400/mo
tirzepatide

'$1,400/mo*' on /products/mounjaro.

Monthly planCompounded
$1400/mo
tirzepatide

'$1,400/mo*' on /products/zepbound. Foundayo (orforglipron) pill also listed but 'Unavailable' — price not published.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

SkinnyRx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

SkinnyRx

7.6/10

Overall

NewSelf

8.3/10

Value25%

8.0A
vs
B
9.0

Effectiveness25%

8.5A
vs
B
8.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

5.8A
vs
B
8.3

Accessibility10%

6.5A
vs
B
8.5

Support10%

8.4A
vs
B
7.9

Features & Coverage

FeatureSkinnyRxNewSelf
Starting Price$149.25/mo$100/mo
Features3 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA Warnings1 warningNone

About SkinnyRx

Telehealth weight-loss provider offering compounded semaglutide and tirzepatide (injectable, with a microdosing option) prescribed by licensed US clinicians, with the consult and free overnight shipping bundled into a monthly cash price.

Read our full SkinnyRx review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

SkinnyRx

What we like

  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access
  • Tiered monthly pricing starting at $199/month
  • Licensed US clinicians on every prescription
  • Discreet shipping included; cancel anytime

Watch-outs

  • Limited public information on program details
  • States_available not publicly disclosed — gated behind signup intake

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: SkinnyRx

SkinnyRx is our recommended choice here, particularly for mainstream telehealth GLP-1 access. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose SkinnyRx if…

You want mainstream telehealth GLP-1 access and a starting price around $149.25/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Budget-conscious shoppers

8.0

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Mainstream telehealth GLP-1 access

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Mainstream telehealth GLP-1 access

SkinnyRx vs NewSelf: FAQ

Key terms, explained

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