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ShedRx vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
ShedRx logo

ShedRx

8.0
★★★★4/5

Best for: mainstream telehealth GLP-1 access

Visit ShedRx
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

ShedRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $169/mo, and ShedRx is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

ShedRx

InjectableCompounded
$199$159/mo
Save 20% right now
semaglutide

$199 1-month / $179 6-month / $159 12-month plan; promo_price = 12-month commitment rate, not a temporary promo

DropsCompounded
$229/mo
semaglutide

Starting at $229/month; 'Medication and supplies included | Member support | Free shipping' (up from $199 in our record)

LozengesCompounded
$199/mo
semaglutide

Starting at $199/month, month-to-month; free shipping stated (replaces our obsolete 'Oral $349' row)

InjectableCompounded
$299$239/mo
Save 20% right now
tirzepatide

$299 1-month / $269 6-month / $239 12-month plan; promo_price = 12-month commitment rate

Daily pillCompounded · oral
$149/mo
orforglipron

NEW product. $149/mo medication (cash pay, paid to dispensing pharmacy) + $125/mo Shed membership and provider fee

Pen weekly / pill dailyCompounded
$149/mo
semaglutide

Page shows BOTH: FAQ 'starts at $149 (pill) and $199 (pen)... new patients using cash pay' + '$99 Shed membership', while hero states '$349-499 for the medication' + '$125/month Shed Membership'. Medication purchased directly via NovoCare; membership fee inconsistency ($99 vs $125) on same page

VialCompounded
$349/mo
tirzepatide

FAQ: 'starts at $349 per month for new patients using cash pay' + $99 membership per FAQ ($125/mo per hero); medication purchased directly via LillyDirect

DailyCompounded · oral
$169/mo
metformin + naltrexone + topiramate

Starting at $169/month; 'Includes 2 Health Coaching sessions per month'

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

ShedRx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

ShedRx

8.0/10

Overall

NewSelf

8.3/10

Value25%

7.5A
vs
B
9.0

Effectiveness25%

9.0A
vs
B
8.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.3

Accessibility10%

7.5A
vs
B
8.5

Support10%

8.0A
vs
B
7.9

Features & Coverage

FeatureShedRxNewSelf
Starting Price$169/mo$100/mo
Features4 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About ShedRx

Telehealth provider offering compounded GLP-1 medications in injectable, lozenge, and drop formats.

Read our full ShedRx review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

ShedRx

What we like

  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access
  • Multiple administration formats

Watch-outs

  • Limited public information on program details

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: ShedRx

ShedRx is our recommended choice here, particularly for mainstream telehealth GLP-1 access. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose ShedRx if…

You want mainstream telehealth GLP-1 access and a starting price around $169/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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7.8

Yucca Health

Mainstream telehealth GLP-1 access

7.7

TrimRx

Best overall value

7.6

Sprout Health

LegitScript-verified compounded GLP-1 via named pharmacies

ShedRx vs NewSelf: FAQ

Key terms, explained

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