Riovie vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.7 out of 10), and Riovie costs less for compounded semaglutide (about $360 a year less).
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Key differences
- Price
- Riovie $149/mo vs Vytora Health $179/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $360 a year less with Riovie)
- Coverage
- Riovie 50 states; Vytora Health 50 states + DC (only Vytora Health: District of Columbia)
- Included
- Riovie: medication, clinician visits, shipping; Vytora Health: medication, clinician visits, shipping
Riovie
Best for low published compounded GLP-1 prices, injection or tablet, with B12 or glycine at no extra cost
semaglutide
$149
Our score 7.7/10
Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Riovie
Vytora Health
Price
Semaglutide / month
Better on this row: $149/mo
$179/mo
Semaglutide / year (modeled)
Better on this row: $1,788
$2,148
Tirzepatide / month
Better on this row: $209/mo
$249/mo
Tirzepatide / year (modeled)
Better on this row: $2,508
$2,988
Oral semaglutide / month
$209/mo
Not listed
Oral tirzepatide / month
$259/mo
Not listed
Brand Zepbound / Mounjaro / month
Not listed
$1,399/mo
Coverage
State availability
50 states
50 states + DC
Oral option listed
Yes
Not listed
Brand-name access listed
Not listed
Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
Month-to-month, 3-month or 6-month plans that renew automatically; a 3- or 6-month term's fee is non-refundable once it begins
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Charges are final once processed, except a refund for the unprovided part if a provider finds you ineligible, and replacement for pharmacy errors; medication is non-refundable once dispensed or shipped
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
FDA warning letters
None on record
None on record
Provider facts checked
November 2026
October 2026
Show where they differ by stateHide state lists
Only Vytora Health (DC)
- District of Columbia
Every dose and plan: Riovie · Vytora Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Riovie if…
- About $360 a year less than Vytora Health for compounded semaglutide at standing prices
- Lists oral compounded semaglutide and oral compounded tirzepatide, which Vytora Health doesn't price
- Every plan price is on the treatment pages before you start, monthly and 3-month
What to weigh up
- Not available in District of Columbia
- The lower 3-month rates lock you into a 3-month term, and that term's fee is not refundable once it starts
Choose Vytora Health if…
- Lists brand-name Zepbound / Mounjaro, which Riovie doesn't price
- Serves District of Columbia, where Riovie doesn't
- Both compounded and brand-name options on one platform
What to weigh up
- About $360 a year more than Riovie for compounded semaglutide
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Riovie
7.7/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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From $79/mo (sale price)
Get started →Gala
Compounded semaglutide or tirzepatide at one all-doses price on a yearly plan, with free shipping
Read full review →From $129/mo (starting dose)
Get started →Found
Medication-included compounded GLP-1 from $169/mo on a 12-month prepaid plan, plus brand insurance help
Read full review →From $169/mo (12-month plan rate)
Get started →Riovie vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.