Rehydra+ Wellness vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Rehydra+ Wellness
Best for: low starting-tier subscription pricing, if you can confirm it covers your state
Visit Rehydra+ Wellness →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Rehydra+ Wellness and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $119/mo, and NewSelf edges ahead overall (8.3 vs 6.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Rehydra+ Wellness
Subscription dose ladder: Tier 1 $119, Tier 2 $169, Tier 3 $229 per month. One-time non-subscription vials start at $149; a separate 2.5 mg listing runs $399-$479.
Subscription dose ladder: Tier 1 $169, Tier 2 $289, Tier 3 $419 per month. One-time non-subscription vials start at $219.
NewSelf
All dosages same price
All dosages same price
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 440+ providers' prices on their own sites and email you when tracked prices move.
What’s included
Rehydra+ Wellness
Inclusions not disclosed.
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Rehydra+ Wellness
6.6/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Rehydra+ Wellness | NewSelf |
|---|---|---|
| Starting Price | $119/mo | ✓$100/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Rehydra+ Wellness
Rehydra+ Wellness is a San Antonio, Texas telehealth brand that grew out of a mobile IV therapy business run by paramedics and nurses. It sells compounded semaglutide and tirzepatide on tiered subscriptions that rise with dose, alongside testosterone therapy, NAD+, a lipotropic Lipo-Plus injection and a broad peptide catalogue including BPC-157, KPV, MOTS-C, tesamorelin, sermorelin and GHK-Cu. Consultations are free, prices are published on the storefront, and financed payment plans are offered. The company says it serves 20 states but does not list them.
Read our full Rehydra+ Wellness review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Rehydra+ Wellness
What we like
- Tier 1 subscription pricing is genuinely low, at $119/mo semaglutide and $169/mo tirzepatide, below the compounded market median.
- Publishes a real phone and text line, (210) 560-0228, plus a named staff email, which many compounded-GLP-1 sites do not.
- Catalogue runs well beyond GLP-1: testosterone therapy, NAD+, and eight named peptides including BPC-157, KPV, MOTS-C and tesamorelin.
- Consultation is free and financed payment plans are offered, so the entry cost is low.
Watch-outs
- No legal entity is named anywhere; the Terms identify only the brand "Rehydra+", with no LLC or corporation behind it.
- Says it serves 20 states but never lists them, so you cannot confirm coverage before starting an intake.
- The LegitScript badge is a self-hosted image linking to the generic checker form; no certification record could be confirmed.
- All prescription sales are final once shipped, and neither the compounding pharmacy nor the provider network is named.
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Rehydra+ Wellness with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Rehydra+ Wellness remains a solid alternative, especially if you're looking for low starting-tier subscription pricing, if you can confirm it covers your state.
Choose Rehydra+ Wellness if…
You want low starting-tier subscription pricing, if you can confirm it covers your state and a starting price around $119/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Care Bare Rx
LGBTQ+-inclusive compounded GLP-1 telehealth
From $199/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →MEDVi
Switching between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →Rehydra+ Wellness vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Rehydra+ Wellness and NewSelf head-to-heads in the same category.
- Rehydra+ Wellness vs Amazon One Medical
- Rehydra+ Wellness vs Vytora Health
- Rehydra+ Wellness vs CoreAge Rx
- NewSelf vs EverSlim
- NewSelf vs Found
- NewSelf vs Elara Health and Wellness
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.