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ReflexMD vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
ReflexMD logo

ReflexMD

7.0
★★★3.5/5

Best for: comprehensive concierge care

Visit ReflexMD
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

ReflexMD and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

ReflexMD

Compounded (flat-rate, all doses)Compounded
$199/mo
semaglutide

HOT20: 20% off 1- and 3-month plans

Compounded (flat-rate, all doses)Compounded
$297/mo
tirzepatide

HOT20: 20% off 1- and 3-month plans

Weight Control oral tablets (flat-rate)oral
$199/mo
semaglutide

Oral Tablets; HOT20: 20% off 1- and 3-month plans

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

ReflexMD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

ReflexMD

7.0/10

Overall

NewSelf

8.3/10

Value25%

6.0A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.3

Accessibility10%

7.5A
vs
B
8.5

Support10%

7.4A
vs
B
7.9

Features & Coverage

FeatureReflexMDNewSelf
Starting Price$199/mo$100/mo
Features3 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About ReflexMD

Telehealth weight loss provider with promotional first-month pricing and flat all-inclusive program rates.

Read our full ReflexMD review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

ReflexMD

What we like

  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access
  • Flat-rate pricing: same monthly price at every dose

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out ReflexMD with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. ReflexMD remains a solid alternative, especially if you're looking for comprehensive concierge care.

Choose ReflexMD if…

You want comprehensive concierge care and a starting price around $199/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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ReflexMD vs NewSelf: FAQ

Key terms, explained

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