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PreventiveMD vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
PreventiveMD logo

PreventiveMD

7.8
★★★3.9/5

Best for: compounded GLP-1s from $83/mo all-in, with brand upgrade paths

Visit PreventiveMD
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

PreventiveMD and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, PreventiveMD starts lower at $83/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

PreventiveMD

StartingCompounded
$83/mo
semaglutide

'As low as $83/mo, all-in' — homepage price, live-verified 2026-07-10

StartingCompounded
$97/mo
tirzepatide

'As low as $97/mo, all-in' — homepage price, live-verified 2026-07-10

Wegovy (brand)Brand-name
$149/mo
semaglutide

Medication starts at $149/mo; a separate $49/mo membership fee applies to brand plans

Foundayo (brand)Brand-name
$149/mo
orforglipron

Medication starts at $149/mo; a separate $49/mo membership fee applies to brand plans

Zepbound (brand)Brand-name
$299/mo
tirzepatide

Medication starts at $299/mo; a separate $49/mo membership fee applies to brand plans

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

PreventiveMD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

PreventiveMD

7.8/10

Overall

NewSelf

8.3/10

Value25%

8.5A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.3

Accessibility10%

7.5A
vs
B
8.5

Support10%

7.4A
vs
B
7.9

Features & Coverage

FeaturePreventiveMDNewSelf
Starting Price$83/mo$100/mo
Features8 features6 features
States Available3649
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted✓ Yes
FDA WarningsNone1 warning

About PreventiveMD

PreventiveMD is a physician-guided telehealth platform for GLP-1 weight loss and peptide therapy, offering compounded semaglutide from $83/mo all-in and compounded tirzepatide from $97/mo all-in, plus brand Wegovy, Zepbound, and Foundayo on a membership model. A US-licensed provider reviews each request within 24 hours; approved medication ships to your door with ongoing care through an online portal.

Read our full PreventiveMD review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

PreventiveMD

What we like

  • Compounded semaglutide from $83/mo and tirzepatide from $97/mo, billed as one all-in monthly price
  • Brand Wegovy, Zepbound, and Foundayo (oral GLP-1) available on the same platform
  • US-licensed provider reviews requests within 24 hours — no video visit required
  • You aren't charged until a provider approves; checkout places an authorization hold only
  • LegitScript-certified; works exclusively with state-licensed US 503A compounding pharmacies
  • HSA/FSA-eligible with receipts you can submit to your insurer
  • Publishes its state-availability list openly on the site

Watch-outs

  • Individual compounding pharmacy partners are not publicly named
  • Not available in 14 states + DC, including New York, New Jersey, Virginia, and Wisconsin
  • Brand Wegovy, Zepbound, and Foundayo require a $49/mo membership fee on top of medication cost
  • 'As low as' pricing — actual monthly cost can be higher depending on your plan
  • Orders become non-refundable once provider review or pharmacy fulfillment begins

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out PreventiveMD with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. PreventiveMD remains a solid alternative, especially if you're looking for compounded GLP-1s from $83/mo all-in, with brand upgrade paths.

Choose PreventiveMD if…

You want compounded GLP-1s from $83/mo all-in, with brand upgrade paths and a starting price around $83/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Direct Meds

Listed for disclosure only — see its FDA warning and BBB complaints first

7.6

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8.0

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Brand-name GLP-1s at cash prices, no compounding

PreventiveMD vs NewSelf: FAQ

Key terms, explained

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.