PrescribedRX vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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PrescribedRX
Best for people who want compounded GLP-1 weight loss inside a broader men's and women's telehealth brandStarting at $189/mo
Amazon One Medical
Best for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savingsStarting at $149/mo
Side-by-Side Comparison
| Feature | PrescribedRX | Amazon One Medical |
|---|---|---|
| Overall Score | 6.8/10 | ✓8.7/10 |
| Starting Price | $189/mo | ✓$149/mo |
| Editorial Rating | 3.4 ★ /5 | ✓4.4 ★ /5 |
| Features | ✓8 features | 6 features |
| States Available | 0 | ✓50 |
| Compounded | — | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
PrescribedRX
What we like
- Compounded semaglutide ($189/mo) and tirzepatide ($276/mo) injectables, with lower per-month pricing on the 3-month plans ($176 and $233/mo)
- Clear, upfront plan pages showing monthly and multi-month pricing with no surprise fees
- Care from licensed US providers with monthly home delivery and ongoing dose support
- Bilingual English/Spanish site and a broader telehealth menu (TRT, longevity, hair, sexual health) for people who want more than weight loss
Watch-outs
- Doesn't publish the states it serves — you only learn eligibility after starting the intake
- Compounding pharmacies aren't named on the site
- Mid-range pricing — cheaper compounded GLP-1 options exist and the 3-month discount is modest
- Compounded semaglutide and tirzepatide injectables only — no brand-name or oral options
- Self-hosted affiliate program (not a vetted network); Florida/Palm Beach framing suggests a regional lean
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out PrescribedRX with a higher overall score of 8.7/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. PrescribedRX remains a solid alternative, especially if you're looking for people who want compounded GLP-1 weight loss inside a broader men's and women's telehealth brand.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.