PlexusDx vs Willow
In our scoring, Willow edges ahead overall (7.2 vs 7.0 out of 10).
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Key differences
- Price
- PlexusDx $129/mo no prepay listed; Willow $299/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- PlexusDx 50 states; Willow 37 states (only PlexusDx: Alabama, Alaska, Arkansas and 10 more)
- Included
- PlexusDx: medication, clinician visits; Willow: medication, clinician visits, shipping
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10
Willow
Affiliate partnerBest for needle-free compounded semaglutide or tirzepatide tablets
semaglutide
$299
starting dose
Our score 7.2/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
PlexusDx
Willow
Price
Semaglutide / month
$129/mo
microdose plan
$299/mo
starting dose
Semaglutide / year (modeled)
$1,548
$3,588
Tirzepatide / month
$249/mo
starting dose
$399/mo
starting dose
Tirzepatide / year (modeled)
$2,988
$4,788
Oral semaglutide / month
Not listed
$299/mo
starting dose
Oral tirzepatide / month
Not listed
$399/mo
starting dose
Coverage
State availability
50 states
37 states
Oral option listed
Not listed
Yes
Included in the price
Medication, clinician visits
Medication, clinician visits, shipping
FSA/HSA accepted
Not listed
Yes
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
Monthly auto-renewing plan; no minimum term stated. 'Your program renews automatically so you never miss a dose.'
Refunds
Not disclosed
'If you cancel before your prescription is sent to the pharmacy, you'll receive a full refund within 5-10 business days.' Terms: 'charges are non-refundable once incurred' and prescription products 'are not returnable'.
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
October 2026
Show where they differ by stateHide state lists
Only PlexusDx (13 states)
- Alabama
- Alaska
- Arkansas
- Kansas
- Louisiana
- Mississippi
- New Mexico
- North Dakota
- Rhode Island
- South Dakota
- Utah
- Vermont
- West Virginia
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose PlexusDx if…
- Serves 13 states that Willow doesn't
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
What to weigh up
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
Choose Willow if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which PlexusDx doesn't price
- Accepts FSA/HSA cards
- All-in plan price covers the medication, doctor evaluation, unlimited doctor messaging and shipping
What to weigh up
- Not available in 13 states that PlexusDx serves
- Pricier than many compounded programs: $299/mo for semaglutide and $399/mo for tirzepatide
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
PlexusDx
7.0/10
Willow
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Luvo Health
Compounded and brand GLP-1s, oral tablets and microdosing on one public price list
Read full review →From $209/4 wks (billed per 4 weeks)
Get started →From $99/mo (“starting at” price)
Get started →Gala
Compounded semaglutide or tirzepatide at one all-doses price on a yearly plan, with free shipping
Read full review →From $129/mo (starting dose)
Get started →PlexusDx vs Willow: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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