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PepHaūs vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
PepHaūs logo

PepHaūs

7.6
★★★3.8/5

Best for: all-inclusive compounded GLP-1 pricing shipped nationwide

Visit PepHaūs
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery

Visit Amazon One Medical

PepHaūs and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $152/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

PepHaūs

Compounded SemaglutideCompounded
$152/mo
semaglutide

From $152/mo on quarterly plan ($179/mo otherwise)

Compounded TirzepatideCompounded
$215/mo
tirzepatide

From $246/mo

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

PepHaūs

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

PepHaūs

7.6/10

Overall

Amazon One Medical

8.5/10

Value25%

8.0A
vs
B
8.5

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.8

Accessibility10%

8.0A
vs
B
9.5

Support10%

7.4A
vs
B
8.0

Features & Coverage

FeaturePepHaūsAmazon One Medical
Starting Price$152/mo$149/mo
Features6 features6 features
States Available5050
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About PepHaūs

PepHaūs is a telehealth pharmacy offering compounded GLP-1 weight-loss treatment — semaglutide from $152/mo and tirzepatide from $246/mo — prescribed by U.S.-licensed providers and shipped from 503A compounding pharmacies. Its pitch is all-inclusive pricing: the medication, medical visit, and shipping are bundled into one cost, with an extra 15% off on quarterly plans. It also offers NAD+, sermorelin, and glutathione alongside weight loss.

Read our full PepHaūs review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

PepHaūs

What we like

  • All-inclusive pricing — medication, medical visit, and shipping bundled into one cost
  • Compounded semaglutide from $152/mo (quarterly) and tirzepatide from $246/mo
  • LegitScript-certified (#50233613); 503A-compounded medication
  • Ships to all 50 states from U.S.-licensed 503A pharmacies
  • Quick online intake with 24-hour provider review

Watch-outs

  • Compounding pharmacy partners aren't named on the marketing site
  • Pricing is customized per patient, so your final cost can vary from the advertised 'from' rates
  • No published individual clinician or medical-director names
  • Newer multi-vertical brand (also NAD+, sermorelin, glutathione) with a limited weight-loss track record

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out PepHaūs with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. PepHaūs remains a solid alternative, especially if you're looking for all-inclusive compounded GLP-1 pricing shipped nationwide.

Choose PepHaūs if…

You want all-inclusive compounded GLP-1 pricing shipped nationwide and a starting price around $152/mo.

Choose Amazon One Medical if…

You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.

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PepHaūs vs Amazon One Medical: FAQ

Amazon One Medical is cheaper. Its lowest ongoing monthly cash price is $149/mo, compared with $152/mo for PepHaūs. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Amazon One Medical scores higher overall at 8.5/10 versus 7.6/10, and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. That said, PepHaūs is a better fit if you want all-inclusive compounded GLP-1 pricing shipped nationwide.
PepHaūs and Amazon One Medical both list availability in 50 states.
Neither PepHaūs nor Amazon One Medical is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

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Continue exploring PepHaūs and Amazon One Medical head-to-heads in the same category.

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.