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OzielRx vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
OzielRx logo

OzielRx

8.0
★★★★4/5

Best for: the cheapest flat-rate compounded GLP-1 with no membership fee

Visit OzielRx
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery

Visit Amazon One Medical

OzielRx and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, OzielRx starts lower at $79/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 8.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

OzielRx

Any dose, flat (1-month or 3-month plan)Compounded
$79$69/mo
Save 13% right now
semaglutide

Verbatim: 'Semaglutide is $79 for one month ($207 for three)'. The $69/mo figure is the 3-month plan, paid as a single $207 charge up front -- not a lower monthly bill. Shown against a struck-through '$299 retail'. Same price at every dose.

Any dose, flat (1-month or 3-month plan)Compounded
$129$119/mo
Save 8% right now
tirzepatide

Verbatim: 'Tirzepatide is $129 for one month ($357 for three)'. The $119/mo figure is the 3-month plan, paid as a single $357 charge up front. Shown against a struck-through '$349 retail'. Same price at every dose.

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

OzielRx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

OzielRx

8.0/10

Overall

Amazon One Medical

8.5/10

Value25%

9.3A
vs
B
8.5

Effectiveness25%

8.2A
vs
B
8.5

User Experience15%

7.8A
vs
B
8.0

Trust & Safety15%

7.0A
vs
B
8.8

Accessibility10%

7.2A
vs
B
9.5

Support10%

7.0A
vs
B
8.0

Features & Coverage

FeatureOzielRxAmazon One Medical
Starting Price$79/mo$149/mo
Features3 features6 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About OzielRx

OzielRx (ozielrx.com) is a telehealth platform operated by OzielRx LLC selling compounded semaglutide and tirzepatide as flat-priced one-month or three-month plans. It charges no membership or consultation fee, holds the same price at every dose, and includes free shipping on every plan.

Read our full OzielRx review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

OzielRx

What we like

  • Among the cheapest compounded GLP-1 pricing we track — $79 for a month of semaglutide, $129 for tirzepatide
  • No membership fee and no consultation fee, stated plainly on the homepage
  • Same price at every dose, so titrating up does not raise the bill
  • Free shipping on every plan, and the eligibility assessment needs no card
  • Full refund if a provider decides treatment is not appropriate, typically within 5 business days

Watch-outs

  • Marketed as a one-time purchase where 'nothing renews', but the site's own policy text describes canceling before the next renewal
  • The three-month price is a single up-front charge, not a lower monthly bill
  • Compounding pharmacies are not named anywhere on the site
  • State availability is not published

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out OzielRx with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. OzielRx remains a solid alternative, especially if you're looking for the cheapest flat-rate compounded GLP-1 with no membership fee.

Choose OzielRx if…

You want the cheapest flat-rate compounded GLP-1 with no membership fee and a starting price around $79/mo.

Choose Amazon One Medical if…

You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.

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7.7

TrimRx

Best overall value

7.6

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LegitScript-verified compounded GLP-1 via named pharmacies

7.5

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OzielRx vs Amazon One Medical: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.