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Omzo vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Omzo logo

Omzo

6.9
★★★3.5/5

Best for: Clinician-guided compounded GLP-1 with free delivery and FSA/HSA

Visit Omzo
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery

Visit Amazon One Medical

Omzo and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $179/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Omzo

Weekly injection — 'starting at'compounded injection
$179/mo
semaglutide
Weekly injection — 'starting at'compounded injection
$279/mo
tirzepatide

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Omzo

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Omzo

6.9/10

Overall

Amazon One Medical

8.5/10

Value25%

6.5A
vs
B
8.5

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

6.5A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
8.8

Accessibility10%

7.5A
vs
B
9.5

Support10%

7.0A
vs
B
8.0

Features & Coverage

FeatureOmzoAmazon One Medical
Starting Price$179/mo$149/mo
Features8 features6 features
States AvailableNot disclosed50
Compounded
Brand Name✓ Yes
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About Omzo

Omzo is a multi-pillar telehealth service (weight loss, women's hormone health, sexual health, hair, skin, daily health) offering clinician-guided compounded GLP-1 — semaglutide and tirzepatide — with free discreet delivery and FSA/HSA eligibility. Medications are filled by an independent state-licensed compounding pharmacy. Pricing is not published on the marketing site (it appears after the intake quiz), and the company does not name its legal entity, pharmacy partner, or state-availability list.

Read our full Omzo review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Omzo

What we like

  • Compounded GLP-1 (semaglutide and tirzepatide) with clinician guidance
  • Free, discreet delivery on all treatments
  • FSA/HSA eligible
  • Multi-pillar: also women's hormone, sexual health, hair, skin, and daily health

Watch-outs

  • Pricing not published on the site — shown only after the intake quiz
  • Compounding pharmacy partner not named (states only 'independent state-licensed')
  • States of operation not published
  • Not LegitScript-certified (no certification displayed)
  • Legal entity not named; governing law given only as 'the state in which Omzo operates'

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Omzo with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Omzo remains a solid alternative, especially if you're looking for Clinician-guided compounded GLP-1 with free delivery and FSA/HSA.

Choose Omzo if…

You want Clinician-guided compounded GLP-1 with free delivery and FSA/HSA and a starting price around $179/mo.

Choose Amazon One Medical if…

You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.

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Omzo vs Amazon One Medical: FAQ

Amazon One Medical is cheaper. Its lowest ongoing monthly cash price is $149/mo, compared with $179/mo for Omzo. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Amazon One Medical scores higher overall at 8.5/10 versus 6.9/10, and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. That said, Omzo is a better fit if you want Clinician-guided compounded GLP-1 with free delivery and FSA/HSA.
Amazon One Medical lists availability in 50 states, while Omzo's state list is not publicly listed.
Neither Omzo nor Amazon One Medical is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

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Continue exploring Omzo and Amazon One Medical head-to-heads in the same category.

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.