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Oak vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Oak logo

Oak

8.1
★★★★4.1/5

Best for: compounded semaglutide and tirzepatide at a flat monthly price

Visit Oak
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical

Oak and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Oak starts lower at $119/mo versus $149/mo, and Oak is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Oak

Starting (flat across all dosages)Compounded
$119/mo
semaglutide

Hero + product card: 'Semaglutide from $119' / 'Most Affordable Semaglutide As low as $119 /mo'. Old code OAKNEW50 no longer on site; a '$200 off — new patient offer' is advertised with no published terms or resulting price (quiz-gated), so promo price is not published. Site is internally inconsistent elsewhere ($133 meta description, $167 compare table, $190 on /weightloss) — hero pricing matches

Starting (flat across all dosages)Compounded
$185/mo
tirzepatide

Hero + product card: 'Tirzepatide from $185' / 'Most Popular Tirzepatide As low as $185 /mo'. Same flat 'One price · All dosages · No subscriptions' model; $200-off new-patient offer advertised without published mechanics — final checkout price quiz-gated, not published.

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Oak

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Oak

8.1/10

Overall

Amazon One Medical

8.5/10

Value25%

9.0A
vs
B
8.5

Effectiveness25%

8.0A
vs
B
8.5

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.8

Accessibility10%

7.5A
vs
B
9.5

Support10%

7.9A
vs
B
8.0

Features & Coverage

FeatureOakAmazon One Medical
Starting Price$119/mo$149/mo
Features4 features6 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Oak

Telehealth provider offering compounded GLP-1 medications (semaglutide and tirzepatide) operated by Oak Longevity Holdings Corp. with prescriptions issued through NVP Medical Group, P.A.

Read our full Oak review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Oak

What we like

  • Both compounded semaglutide ($119/mo) and tirzepatide ($185/mo) on a single platform
  • $200-off new-patient offer advertised — final discounted price is shown after the intake quiz
  • LegitScript-certified pharmacy network
  • No video call required for initial approval; flat per-month pricing across all dose strengths

Watch-outs

  • Pharmacy partners are not publicly named on the marketing site (material gap for YMYL disclosure)
  • Operates in 45 states per Terms of Use, but the public state list is gated behind the signup intake
  • No brand-name Wegovy / Zepbound / Mounjaro / Ozempic available — compounded only
  • Fees are non-refundable per Terms of Use; binding arbitration under Delaware law

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Oak

Oak is our recommended choice here, particularly for compounded semaglutide and tirzepatide at a flat monthly price. Amazon One Medical is a solid alternative, especially if you want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose Oak if…

You want compounded semaglutide and tirzepatide at a flat monthly price and a starting price around $119/mo.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

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Oak vs Amazon One Medical: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.