NewSelf vs Zappy Health
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
Zappy Health
Best for: people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with dose
Visit Zappy Health →NewSelf and Zappy Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $159/mo, and NewSelf edges ahead overall (8.3 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
Zappy Health
From $159/mo (9-mo); $199 (3-mo); $249 month-to-month; flat across doses
From $299/mo (9-mo); $329 (3-mo); $359 month-to-month; flat across doses
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Zappy Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
Zappy Health
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | Zappy Health |
|---|---|---|
| Starting Price | ✓$100/mo | $159/mo |
| Features | 6 features | ✓8 features |
| States Available | ✓49 | 42 |
| Compounded | ✓ Yes | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About Zappy Health
Zappy Health is a telehealth weight-loss platform offering both compounded and brand-name GLP-1: compounded semaglutide from $159/month and tirzepatide from $299/month, plus brand Wegovy and Zepbound. Pricing is flat — it doesn't rise with your dose — and longer subscriptions cost less. You complete an online visit and a licensed clinician prescribes if appropriate. Zappy operates in about 42 states (not HI, AL, AR, CA, KS, MI, MN or MS). Note that some third-party reports raise pharmacy-sourcing concerns.
Read our full Zappy Health review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Zappy Health
What we like
- Both compounded GLP-1 and brand-name Wegovy/Zepbound available
- Flat pricing that doesn't increase as your dose goes up
- Cheaper on longer subscriptions — compounded semaglutide from $159/month
- Online visit with a licensed clinician; no insurance required
Watch-outs
- Third-party reports of an order arriving with an unlicensed-pharmacy label
- Not available in 8 states (HI, AL, AR, CA, KS, MI, MN, MS)
- Operating legal entity isn't clearly disclosed on the site
- Lowest prices require a 9-month commitment
Our Verdict
NewSelf edges out Zappy Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Zappy Health remains a solid alternative, especially if you're looking for people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with dose.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose Zappy Health if…
You want people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with dose and a starting price around $159/mo.
Ready to start? Vetted GLP-1 providers
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Direct Meds
Listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →NewSelf vs Zappy Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.