NewSelf vs Youth & Soul
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
Youth & Soul
Best for: shoppers who want many treatment categories in one account and are willing to verify claims themselves
Visit Youth & Soul →NewSelf and Youth & Soul are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $149/mo, and NewSelf edges ahead overall (8.3 vs 5.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
Youth & Soul
Compounded semaglutide 0.25mg to 1mg titration with a B12 injection, physician consultation and shipping included.
Higher-dose semaglutide 1mg to 2.4mg with metformin 500mg and a B12 plus Lipo-C injection.
Compounded tirzepatide 2.5mg to 15mg with metformin XR, B12 plus MIC and an NAD+ nasal spray.
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Youth & Soul
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
Youth & Soul
5.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | Youth & Soul |
|---|---|---|
| Starting Price | ✓$100/mo | $149/mo |
| Features | ✓6 features | 4 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About Youth & Soul
Ten-vertical telehealth marketplace selling compounded GLP-1 tiers alongside HRT, ED, nootropics and peptides, running on the Bask Health platform.
Read our full Youth & Soul review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Youth & Soul
What we like
- Three GLP-1 tiers priced openly, with the dose range and every included component listed per tier
- Full refund advertised if you are not approved
- Physician consultation, prescription and shipping stated as included in the plan price
- Ten treatment verticals under one account, from GLP-1 to HRT, peptides and mental health
Watch-outs
- Describes its compounded medications as FDA-Approved Compounds, which is false: compounded drugs are not FDA-approved
- Presents scraped third-party comments as testimonials, several using Reddit usernames and some describing brand Wegovy or Mounjaro
- Its own copy promises never to fabricate testimonials while displaying those scraped comments
- Homepage trust counters render as 0K+ medical professionals, 0.0M+ patients and 0M+ successful orders
- Labels its compounded tirzepatide a Mounjaro compound, conflating a compounded drug with the brand
- Uses artificial scarcity: Currently 3 Telemed Doctor Consultations Available Today
- No state list, no named pharmacy and no named legal entity anywhere on the site
Our Verdict
NewSelf edges out Youth & Soul with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Youth & Soul remains a solid alternative, especially if you're looking for shoppers who want many treatment categories in one account and are willing to verify claims themselves.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose Youth & Soul if…
You want shoppers who want many treatment categories in one account and are willing to verify claims themselves and a starting price around $149/mo.
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bmiMD
Mainstream telehealth GLP-1 access
From $99/mo
Get started →RNK Health
Compounded GLP-1 alongside NAD+, peptide and longevity add-ons
From $197/mo
Get started →Wellorithm
Compounded GLP-1 access with oral tablet options across 49 states
From $147/mo
Get started →NewSelf vs Youth & Soul: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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