NewSelf vs Willow
Our featured pick: Willow (affiliate partner). In our scoring, NewSelf scores 8.2 and Willow 7.2 out of 10.
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Key differences
- Price
- NewSelf $100/mo on a 3-month prepaid plan; Willow $299/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- NewSelf 48 states + PR; Willow 36 states (only NewSelf: Alabama, Alaska, Arkansas and 10 more)
- Included
- NewSelf: medication, clinician visits, shipping; Willow: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: NewSelf 1, Willow none

NewSelf
Best for lowest-cost compounded GLP-1 at one price for every dose, if a 3-month commitment works for you
semaglutide
$100
on a 3-month prepaid plan
Our score 8.2/10
Willow
Affiliate partnerBest for needle-free compounded semaglutide or tirzepatide tablets
semaglutide
$299
Our score 7.2/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
NewSelf
Willow
Price
Semaglutide / month
$100/mo
on a 3-month prepaid plan
$299/mo
Semaglutide / year (modeled)
$1,200
$3,588
Tirzepatide / month
$144/mo
on a 3-month prepaid plan
$399/mo
Tirzepatide / year (modeled)
$1,728
$4,788
Oral semaglutide / month
Not listed
$299/mo
Oral tirzepatide / month
Not listed
$399/mo
Coverage
State availability
48 states + PR
36 states
Oral option listed
Not listed
Yes
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
FSA/HSA accepted
Not listed
Yes
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
No
Better on this row: Yes
Minimum commitment
3-month plan for the listed price
Monthly auto-renewing plan; no minimum term stated. 'Your program renews automatically so you never miss a dose.'
Refunds
No refunds after the doctor visit; full refund if the doctor declines; $99 fee if you cancel before the visit
'If you cancel before your prescription is sent to the pharmacy, you'll receive a full refund within 5-10 business days.' Terms: 'charges are non-refundable once incurred' and prescription products 'are not returnable'.
Early-cancellation fee
Yes
Not disclosed
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
October 2026
October 2026
Show where they differ by stateHide state lists
Only NewSelf (12 states + PR)
- Alabama
- Alaska
- Arkansas
- Delaware
- Kansas
- New Mexico
- North Dakota
- PR
- Rhode Island
- South Dakota
- Utah
- Vermont
- West Virginia
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose NewSelf if…
- Serves 12 states + PR that Willow doesn't
- Same price at every dose, so your bill doesn't rise as you titrate up
- No membership fee; the visit, medication and shipping are bundled
What to weigh up
- 1 FDA warning letter on record
- Its $100/mo compounded semaglutide price needs a 3-month prepaid plan
Choose Willow if…
- Its $299/mo compounded semaglutide price needs no prepay; NewSelf's $100 needs a 3-month prepay
- Lists oral compounded semaglutide and oral compounded tirzepatide, which NewSelf doesn't price
- Cancel anytime
What to weigh up
- Not available in 12 states + PR that NewSelf serves
- Pricier than many compounded programs: $299/mo for semaglutide and $399/mo for tirzepatide
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.2/10
Willow
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →NewSelf vs Willow: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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