NewSelf vs WePeptideRx
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
WePeptideRx
Best for: premixed ready-to-inject GLP-1 with microdose protocol options
Visit WePeptideRx →NewSelf and WePeptideRx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $189/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
WePeptideRx
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
WePeptideRx
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
WePeptideRx
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | WePeptideRx |
|---|---|---|
| Starting Price | ✓$100/mo | $189/mo |
| Features | 6 features | ✓8 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About WePeptideRx
WePeptideRx is a provider-guided telehealth platform offering compounded semaglutide and tirzepatide alongside a deep menu of peptide, hormone, hair, and sexual-wellness programs. Its standout is delivery: medications arrive premixed and ready to inject — no bacteriostatic water or sharps container needed — plus flat-rate microdose options. LegitScript-certified and available in 48 states, with intro pricing at $189 the first month (from $249/mo standard).
Read our full WePeptideRx review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
WePeptideRx
What we like
- Pre-mixed ready-to-inject delivery skips the vial reconstitution and sharps hassle of most compounded providers
- Microdose protocols (0.05–0.25 mg sema, 0.5–2.5 mg tirz) suit ultra-low-dose maintenance patients — uncommon in DTC
- 12+ programs under one platform — GLP-1 plus longevity, sexual wellness, and hair
- Physical Boca Raton address, phone, and business hours listed
- LegitScript Certified and publishes the FDA disclaimer
- HSA/FSA accepted (uncommon for DTC compounded GLP-1)
Watch-outs
- Pharmacy partner not named
- 48-state claim, but the specific state list isn't shown on the homepage
- Medical director not named on the homepage
- Telemedicine is outsourced to a third-party provider network rather than in-house staff
- Corporate legal entity and arbitration venue not disclosed
- Microdose tiers require understanding sub-therapeutic dosing — verify clinical fit
Our Verdict
NewSelf edges out WePeptideRx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. WePeptideRx remains a solid alternative, especially if you're looking for premixed ready-to-inject GLP-1 with microdose protocol options.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose WePeptideRx if…
You want premixed ready-to-inject GLP-1 with microdose protocol options and a starting price around $189/mo.
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Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →MEDVi
Patients who want the option to switch between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →Liv Body
Compounded GLP-1 paired with a muscle-preservation supplement stack
From $179/mo
Get started →NewSelf vs WePeptideRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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