NewSelf vs Unique Physique
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
Unique Physique
Best for: Baton Rouge hybrid in-office plus telehealth GLP-1 with a named DO
Visit Unique Physique →NewSelf and Unique Physique are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $195/mo, and NewSelf edges ahead overall (8.3 vs 5.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
Unique Physique
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Unique Physique
What the monthly price covers
Medication
Included
Provider visits
Not disclosed
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
Unique Physique
5.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | Unique Physique |
|---|---|---|
| Starting Price | ✓$100/mo | $195/mo |
| Features | ✓6 features | 1 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About Unique Physique
Unique Physique is a hybrid in-office and telehealth weight-loss clinic in Baton Rouge, Louisiana, with medical oversight from Reena John, DO. Its differentiator is a brick-and-mortar option — free in-office pickup or mail delivery — under a named operating entity, alongside two-tier flat-rate compounded GLP-1 pricing. The flat tiers are $195/mo and $325/mo (every dose included), with brand-name Rx routing to your own pharmacy for $25/mo.
Read our full Unique Physique review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Unique Physique
What we like
- Legal entity disclosed (Unique Physique, LLC) with Louisiana governing law — better than opaque DTC competitors
- Named medical director (Reena John, DO) — uncommon at this price tier
- Brick-and-mortar clinic in Baton Rouge, LA offers an in-person option vs ship-only competitors
- Transparent two-tier flat pricing ($195/mo and $325/mo) — no dose-escalation surprises
- Brand-name routing option ($25/mo) sends an Rx to your own pharmacy for Wegovy/Zepbound/Ozempic/Mounjaro
- Adjunct injectables (Lipo-Mino, NAD+) available for bundled metabolic support
Watch-outs
- GLP-1 drug molecules aren't named on the pricing or service pages — you can't confirm what the $195/mo and $325/mo plans contain without calling
- Pharmacy partner not named — can't verify licensure or 503A vs 503B status
- No FDA compounded-medication disclaimer on any audited page
- States served not listed — only "licensed clinicians in the patient's state"
- Non-refundable per the Terms; medication not picked up within 60 days is discarded with no refund
- Insurance acceptance not addressed; brand-name routing adds a $25/mo fee on top of pharmacy cost
- Lab work requirements not disclosed
Our Verdict
NewSelf edges out Unique Physique with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Unique Physique remains a solid alternative, especially if you're looking for Baton Rouge hybrid in-office plus telehealth GLP-1 with a named DO.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose Unique Physique if…
You want Baton Rouge hybrid in-office plus telehealth GLP-1 with a named DO and a starting price around $195/mo.
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Best overall value
From $135/mo
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LegitScript-verified compounded GLP-1 via named pharmacies
From $149/mo
Get started →NewSelf vs Unique Physique: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.