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NewSelf vs TRYM Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf
VS
TRYM Health logo

TRYM Health

7.5
★★★3.8/5

Best for: low-cost compounded GLP-1 vials shipped nationwide

Visit TRYM Health

NewSelf and TRYM Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, TRYM Health starts lower at $96/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

TRYM Health

Multi-dose vial, all doses (as-low-as)Compounded
$96/mo
semaglutide
Multi-dose vial, all doses (as-low-as)Compounded
$126/mo
tirzepatide

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

TRYM Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

TRYM Health

7.5/10

Value25%

9.0A
vs
B
8.0

Effectiveness25%

8.0A
vs
B
7.5

User Experience15%

8.0A
vs
B
7.0

Trust & Safety15%

8.3A
vs
B
6.8

Accessibility10%

8.5A
vs
B
8.0

Support10%

7.9A
vs
B
7.4

Features & Coverage

FeatureNewSelfTRYM Health
Starting Price$100/mo$96/mo
Features6 features8 features
States Available49Not disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About TRYM Health

TRYM Health (TRYM) is a nationwide telehealth service offering compounded GLP-1 weight-loss medication — semaglutide (~$96/mo, $3.20/day) and tirzepatide (~$126/mo, $4.20/day) — as additive-free multi-dose vials covering all doses, with a starter kit, temperature-controlled shipping, FSA/HSA eligibility, and flexible cancellation. Available in all 50 states; it also offers wellness and hair-care plans. Operated by TRYM Health, Inc.; medications are compounded by unnamed partner pharmacies, and the site shows no LegitScript certification.

Read our full TRYM Health review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

TRYM Health

What we like

  • Affordable compounded GLP-1 — semaglutide ~$96/mo ($3.20/day) and tirzepatide ~$126/mo ($4.20/day)
  • Available in all 50 states with free shipping and FSA/HSA eligibility
  • Multi-dose vials cover all doses up to the maximum; additive-free, with a full starter kit
  • Temperature-controlled insulated shipping and flexible cancellation

Watch-outs

  • Compounding pharmacy partner not named
  • Not LegitScript-certified (no certification displayed)
  • Lowest per-day pricing likely requires a longer prepaid plan commitment
  • Drugs labeled generically as 'GLP-1' / 'GLP-1 + GIP' on the services page rather than named

Our Verdict

Winner: NewSelf

NewSelf edges out TRYM Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. TRYM Health remains a solid alternative, especially if you're looking for low-cost compounded GLP-1 vials shipped nationwide.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose TRYM Health if…

You want low-cost compounded GLP-1 vials shipped nationwide and a starting price around $96/mo.

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NewSelf vs TRYM Health: FAQ

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