NewSelf vs TRT Nation
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →TRT Nation
Best for: Men wanting flat-rate compounded tirzepatide alongside a TRT-focused platform
Visit TRT Nation →NewSelf and TRT Nation are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $219/mo, and NewSelf edges ahead overall (8.3 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
TRT Nation
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
TRT Nation
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
TRT Nation
6.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | TRT Nation |
|---|---|---|
| Starting Price | ✓$100/mo | $219/mo |
| Features | 6 features | ✓7 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About TRT Nation
TRT Nation is a men's telehealth platform focused primarily on testosterone replacement therapy, with compounded GLP-1 weight loss as a secondary vertical. It prescribes compounded tirzepatide at a flat $219/month (any dose), each script compounded with vitamin B12 to ease nausea, plus compounded semaglutide; reported GLP-1 pricing ranges roughly $150 to $400/month. The flat plan includes an initial virtual physician visit, delivery from licensed US compounding pharmacies, and unlimited follow-ups. The pharmacy partner and 503A status are not publicly disclosed.
Read our full TRT Nation review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
TRT Nation
What we like
- Flat $219/mo tirzepatide regardless of dose escalation
- Tirzepatide compounded with B12 to reduce nausea
- Flat plan includes unlimited virtual provider visits
- Fully online intake-to-delivery process
- Compounded from licensed US pharmacies
Watch-outs
- Weight loss is secondary to core TRT business
- Specific pharmacy partner and 503A status not disclosed
- Compounded only; not FDA-approved formulations
- State licensing list not published
Our Verdict
NewSelf edges out TRT Nation with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. TRT Nation remains a solid alternative, especially if you're looking for Men wanting flat-rate compounded tirzepatide alongside a TRT-focused platform.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose TRT Nation if…
You want Men wanting flat-rate compounded tirzepatide alongside a TRT-focused platform and a starting price around $219/mo.
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PeterMD
Men seeking flat-priced compounded GLP-1 access alongside TRT or peptide therapy
From $105/mo
Get started →Care Bare Rx
LGBTQ+-inclusive compounded GLP-1 telehealth
From $199/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →NewSelf vs TRT Nation: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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