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NewSelf vs Trimi Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf
VS
Trimi Health logo

Trimi Health

7.9
★★★★4/5

Best for: budget-conscious shoppers

Visit Trimi Health

NewSelf and Trimi Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Trimi Health starts lower at $99/mo versus $100/mo, and Trimi Health is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

Trimi Health

All doses (flat)Compounded
$175/mo
semaglutide

Billed monthly. Flat price at every dose.

All doses (flat)Compounded
$145/mo
semaglutide

Quarterly plan: billed $435 every 3 months.

All doses (flat)Compounded
$120/mo
semaglutide

Bi-annual plan: billed $720 every 6 months.

All doses (flat)Compounded
$99/mo
semaglutide

Annual plan: billed $1,188 yearly upfront (or BNPL via Affirm/Klarna/Afterpay). This is the advertised headline price.

All doses (flat)Compounded
$235/mo
tirzepatide

Billed monthly. Flat price at every dose.

All doses (flat)Compounded
$199/mo
tirzepatide

Quarterly plan: billed $597 every 3 months.

All doses (flat)Compounded
$175/mo
tirzepatide

6-month plan: billed $1,050 every 6 months.

All doses (flat)Compounded
$125/mo
tirzepatide

Annual plan: billed $1,500 yearly upfront (or BNPL). This is the advertised headline price.

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Trimi Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

Trimi Health

7.9/10

Value25%

9.0A
vs
B
8.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

8.3A
vs
B
7.3

Accessibility10%

8.5A
vs
B
8.0

Support10%

7.9A
vs
B
8.4

Features & Coverage

FeatureNewSelfTrimi Health
Starting Price$100/mo$99/mo
Features6 features3 features
States Available4950
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA Warnings1 warningNone

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About Trimi Health

Telehealth provider offering some of the lowest compounded GLP-1 pricing available.

Read our full Trimi Health review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Trimi Health

What we like

  • Aggressively low monthly pricing
  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access

Watch-outs

  • Limited public information on program details

Our Verdict

Winner: Trimi Health

Trimi Health is our recommended choice here, particularly for budget-conscious shoppers. NewSelf is a solid alternative, especially if you want lowest-cost compounded GLP-1 with pharmacy quality transparency — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose Trimi Health if…

You want budget-conscious shoppers and a starting price around $99/mo.

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7.8

Yucca Health

Mainstream telehealth GLP-1 access

7.7

TrimRx

Best overall value

7.6

Sprout Health

LegitScript-verified compounded GLP-1 via named pharmacies

NewSelf vs Trimi Health: FAQ

Trimi Health is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $100/mo for NewSelf. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
For most people we'd start with Trimi Health, especially if you want budget-conscious shoppers. NewSelf is a strong alternative and may suit you better for lowest-cost compounded GLP-1 with pharmacy quality transparency — weigh the six-dimension breakdown above to decide which fits your priorities.
Trimi Health covers more — 50 states versus 49.
Trimi Health is an affiliate partner (we may earn a commission on sign-ups through our links); NewSelf is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, Trimi Health is cheaper at $99/mo versus $100/mo at NewSelf.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring NewSelf and Trimi Health head-to-heads in the same category.

Or see the full category ranking.

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