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NewSelf vs Thryve

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf
VS
Thryve logo

Thryve

3.3
☆☆☆1.7/5
Visit Thryve

NewSelf and Thryve are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts at $100/mo, and NewSelf edges ahead overall (8.3 vs 3.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

Thryve

Pricing not publicly listed.

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Thryve

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

Thryve

3.3/10

Value25%

9.0A
vs
B
4.0

Effectiveness25%

8.0A
vs
B
4.5

User Experience15%

8.0A
vs
B
2.5

Trust & Safety15%

8.3A
vs
B
1.5

Accessibility10%

8.5A
vs
B
4.0

Support10%

7.9A
vs
B
2.0

Features & Coverage

FeatureNewSelfThryve
Starting Price$100/mo
Features6 features3 features
States Available49Not disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About Thryve

Thryve markets a GLP-1 peptide program for weight loss, starting at $99 a month. The site does not name a specific medication such as semaglutide or tirzepatide, describing its product only as "a peptide currently under clinical research." As of this review the site has no working Terms of Service or Privacy Policy page, and its "Get Started" button does not lead to any signup or intake flow.

Read our full Thryve review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Thryve

What we like

  • Advertises a straightforward starting price of $99/month on the homepage
  • States a weight-loss money-back guarantee on the homepage banner

Watch-outs

  • Does not name the specific medication (e.g., semaglutide, tirzepatide) anywhere on the site
  • No working Terms of Service or Privacy Policy page — the footer links have empty hrefs
  • No functional signup or intake flow found — the "Get Started" button links to an in-page anchor with no matching content
  • Lists a placeholder phone number (tel:+123 12345 67890) instead of real contact info
  • No state-availability, pharmacy-partner, or legal-entity information published
  • Site's own sitemap shows only the homepage and the default WordPress "Hello World" post
  • "Trusted by 20,000+ Members" and a 5-star badge are not linked to any verifiable review platform
  • Describes its product only as "a peptide currently under clinical research," not as an FDA-approved medication

Our Verdict

Winner: NewSelf

NewSelf edges out Thryve with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Thryve remains a solid alternative.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose Thryve if…

You want broader feature coverage.

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7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

NewSelf vs Thryve: FAQ

Key terms, explained

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