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NewSelf vs Superpower

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf
VS
Superpower logo

Superpower

7.1
★★★3.6/5

Best for: Members who want lab testing bundled with a GLP-1 prescription, not just medication

Visit Superpower

NewSelf and Superpower are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

Superpower

Compounded GLP-1, starting dose (billed every 2 months, paid upfront in full)Compounded
$199/mo
semaglutide

Marketing 'from' price on superpower.com/semaglutide; the standalone Marketplace product listing for the same compounded semaglutide shows $229/mo. Separate from the $199/year membership fee.

Ozempic (brand), billed every 2 months, paid upfront in fullBrand-name
$1799/mo
semaglutide

Brand Ozempic 'from' price shown alongside the compounded option on the same page; same bimonthly upfront-billing cadence applies.

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Superpower

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Not disclosed

Lab work

Included

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

Superpower

7.1/10

Value25%

9.0A
vs
B
7.0

Effectiveness25%

8.0A
vs
B
7.0

User Experience15%

8.0A
vs
B
7.0

Trust & Safety15%

8.3A
vs
B
7.0

Accessibility10%

8.5A
vs
B
7.5

Support10%

7.9A
vs
B
7.5

Features & Coverage

FeatureNewSelfSuperpower
Starting Price$100/mo$199/mo
Features6 features7 features
States Available4942
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About Superpower

Superpower is a $199-per-year health membership built around twice-yearly 100+ biomarker lab testing, not a single-purpose GLP-1 shop. Members who are clinically appropriate can add prescription treatments -- including compounded semaglutide or brand-name Ozempic -- through Superpower's in-house Marketplace, billed separately from the membership fee. Pharmacy fulfillment runs through named partners Strive Pharmacy, Belmar Pharmacy, and Progress Pharmacy.

Read our full Superpower review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Superpower

What we like

  • Twice-yearly 100+ biomarker lab testing bundled into every membership, not just a GLP-1 prescription mill
  • Named compounding pharmacy partners: Strive Pharmacy, Belmar Pharmacy, and Progress Pharmacy
  • 30-day money-back guarantee on the GLP-1 medication itself if it isn't a fit
  • Real, claimed Trustpilot profile: 4.6/5 from 309 reviews
  • Both compounded semaglutide and brand-name Ozempic offered on one page
  • Available in 42 of 51 US jurisdictions (50 states + DC) per its own published list
  • 24/7 care team access claimed, plus a published members@superpower.com support contact

Watch-outs

  • Two separate $199 charges with different meanings ($199/year membership vs. 'from $199/month' medication) risk confusing shoppers
  • GLP-1 'from $199/month' is billed every 2 months, paid upfront in full -- not a true monthly charge
  • Marketplace list price for the same compounded semaglutide is $229/mo, above the landing-page 'from' figure
  • $199/year membership fee is non-refundable even though the medication carries a 30-day guarantee
  • LegitScript certification is only a text claim on-site; no verifiable seal or badge image was found
  • No health insurance accepted
  • Mandatory binding arbitration and class-action waiver in the Terms of Service
  • Not available in Alaska, Arkansas, Hawaii, Louisiana, Mississippi, North Dakota, Rhode Island, South Dakota, or Wyoming

Our Verdict

Winner: NewSelf

NewSelf edges out Superpower with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Superpower remains a solid alternative, especially if you're looking for Members who want lab testing bundled with a GLP-1 prescription, not just medication.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose Superpower if…

You want Members who want lab testing bundled with a GLP-1 prescription, not just medication and a starting price around $199/mo.

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6.4

Direct Meds

Listed for disclosure only — see its FDA warning and BBB complaints first

7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

NewSelf vs Superpower: FAQ

Key terms, explained

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