NewSelf vs Spry
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
Spry
Best for: compounded GLP-1 plus anti-aging peptides under one membership
Visit Spry →NewSelf and Spry are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 6.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
Spry
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Spry
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
Spry
6.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | Spry |
|---|---|---|
| Starting Price | ✓$100/mo | $199/mo |
| Features | ✓6 features | 5 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | ✓None | 1 warning |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About Spry
Spry is a weight-loss and anti-aging telehealth platform pairing compounded semaglutide ($199/mo) and tirzepatide ($299/mo) with three longevity peptides — BPC-157, NAD+, and sermorelin ($249–$299/mo). It's LegitScript Certified, names three co-founders, requires no contracts, and has a nurse practitioner review intake within 24 hours. Note: the site shows an "FDA Approved" badge, but compounded GLP-1s are not FDA-approved finished products.
Read our full Spry review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Spry
What we like
- Three named co-founders disclosed (Gabriel Mullins, Sara Yoder, Tyler Bowman) — better-than-average transparency
- Pricing shown on the homepage ($199 semaglutide / $299 tirzepatide / $249–$299 peptides) — no full sign-up wall
- Broader range (2 GLP-1s plus 3 anti-aging peptides) appeals to longevity buyers
- No contracts or commitment required
- LegitScript Certified with a public verification link
- Same-day to 24-hour provider intake review
Watch-outs
- Displays an "FDA Approved" badge though compounded GLP-1s are not FDA-approved finished drugs — potentially misleading
- Intake reviewed by a nurse practitioner, not an MD
- States served not disclosed publicly
- Pharmacy partner not named, and 503A vs 503B designation not specified
- Corporate legal entity not disclosed
- Co-founder credentials not disclosed
- Includes BPC-157, an unregulated peptide with limited human efficacy data, reflecting a functional-medicine slant
Our Verdict
NewSelf edges out Spry with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Spry remains a solid alternative, especially if you're looking for compounded GLP-1 plus anti-aging peptides under one membership.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose Spry if…
You want compounded GLP-1 plus anti-aging peptides under one membership and a starting price around $199/mo.
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PeterMD
Men seeking flat-priced compounded GLP-1 access alongside TRT or peptide therapy
From $105/mo
Get started →Care Bare Rx
LGBTQ+-inclusive compounded GLP-1 telehealth
From $199/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →NewSelf vs Spry: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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