NewSelf vs Shapely
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
Shapely
Best for: Insurance-accepted telehealth: sema $99/mo, tirz $166/mo; CA/FL/NY/TX
Visit Shapely →NewSelf and Shapely are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Shapely starts lower at $99/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
Shapely
Verbatim from semaglutide medication page: 'Starting at $99/month'. Starter 3-month supply at lowest titration dose ($297/quarter). Tiered: ~$139/mo (low-mid dose), ~$179/mo (high dose). Free 2-day shipping; syringes and alcohol pads included. Via state-licensed 503A/503B compounding pharmacy. A separate telehealth recurring plan ($99/mo, $49 first-month promo) is required in addition to the medication cost.
Verbatim from tirzepatide medication page: 'Starting at $166/month'. Starter dose at lowest titration. Tiered: ~$249/mo (low-mid dose), ~$299/mo (high dose). Free 2-day shipping; syringes and alcohol pads included. Via state-licensed 503A/503B compounding pharmacy. Self-pay only for compounded tirz. A separate telehealth recurring plan ($99/mo, $49 first-month promo) is required in addition to the medication cost.
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Shapely
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Included
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
Shapely
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | Shapely |
|---|---|---|
| Starting Price | $100/mo | ✓$99/mo |
| Features | 6 features | ✓8 features |
| States Available | ✓49 | 4 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | 1 warning | ✓None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About Shapely
Shapely is a GLP-1 telehealth platform founded by Dr. Justin Zaghi, MD/MBA, a Harvard-trained physician board-certified in both internal medicine and obesity medicine. The service accepts major PPO insurance and Medicare for brand-name GLP-1s including Wegovy, Ozempic, Zepbound, and Mounjaro, while offering compounded semaglutide from $99/month and compounded tirzepatide from $166/month for self-pay patients — both with free 2-day shipping and supplies included via state-licensed 503A/503B pharmacies.
Read our full Shapely review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Shapely
What we like
- Founded by Dr. Justin Zaghi, MD/MBA — Harvard-trained, board-certified in internal medicine and obesity medicine, with Medical Director Ana Lisa
- Brand-name GLP-1s (Wegovy, Ozempic, Zepbound, Mounjaro, Foundayo) covered by major PPO and Medicare at copay
- Compounded semaglutide from $99/month with free 2-day shipping, syringes, and supplies included via 503A/503B pharmacy
- 1:1 registered dietitian (RDN) and monthly video provider visits included in every plan; unlimited chat and app support
- Cellular smart scale provided to qualifying patients for ongoing weight tracking throughout the program
Watch-outs
- Currently available only in California, Florida, New York, and Texas — 46 states unserved despite announced expansion
- Telehealth subscription ($99/mo self-pay, $49 first-month promo) is charged separately from compounded medication cost
- Labs not included — $75 flat rate for uninsured patients; baseline bloodwork may be required before prescribing
- No LegitScript certification found on any public page
- Compounding pharmacy partner not named publicly; 503A/503B status claimed but specific pharmacy undisclosed
Our Verdict
NewSelf edges out Shapely with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Shapely remains a solid alternative, especially if you're looking for Insurance-accepted telehealth: sema $99/mo, tirz $166/mo; CA/FL/NY/TX.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose Shapely if…
You want Insurance-accepted telehealth: sema $99/mo, tirz $166/mo; CA/FL/NY/TX and a starting price around $99/mo.
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Sesame Care
Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $88/mo
Get started →NewSelf vs Shapely: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.