NewSelf vs RxION Health
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
NewSelf and RxION Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
RxION Health
Regular $199/mo; current promo $107/mo. Consultation + medication + free overnight shipping included.
Regular $299/mo; current promo $183/mo. Consultation + medication + free overnight shipping included.
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 390+ providers' prices on their own sites and email you when tracked prices move.
What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
RxION Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
RxION Health
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | RxION Health |
|---|---|---|
| Starting Price | ✓$100/mo | $199/mo |
| Features | ✓6 features | 5 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About RxION Health
RxION Health offers compounded semaglutide and tirzepatide including microdosing. LegitScript certified. Also offers anti-aging and sexual health treatments.
Read our full RxION Health review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
RxION Health
What we like
- LegitScript Certified
- Offers both semaglutide and tirzepatide, including microdosing
- HIPAA compliant
- States its medications are FDA-regulated
Watch-outs
- No physical address listed
- No named pharmacy partners
- Not available to residents of New Jersey, Alaska, or Mississippi
Our Verdict
NewSelf edges out RxION Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. RxION Health remains a solid alternative, especially if you're looking for pending full pricing verification.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose RxION Health if…
You want pending full pricing verification and a starting price around $199/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
DudeMeds
Men seeking no-fee GLP-1 access with oral and injectable options
From $175/mo
Get started →Yucca Health
Mainstream telehealth GLP-1 access
From $146/mo
Get started →TrimRx
Best overall value
From $135/mo
Get started →NewSelf vs RxION Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring NewSelf and RxION Health head-to-heads in the same category.
- NewSelf vs Amazon One Medical
- NewSelf vs Vytora Health
- NewSelf vs CoreAge Rx
- RxION Health vs EverSlim
- RxION Health vs Found
- RxION Health vs Elara Health and Wellness
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.