NewSelf vs Roen Rx
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
Roen Rx
Best for: patients with insurance seeking brand-name GLP-1 access with compounded fallback
Visit Roen Rx →NewSelf and Roen Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Roen Rx starts lower at $25/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
Roen Rx
Medication price only; a separate Roen Rx membership is required on top.
Medication price only; membership billed separately.
As low as $25 monthly copay with insurance coordination; membership still required.
First month discounted to $39; standard recurring membership rate not published. GLP-1 medications are not included in the membership fee. drug omitted intentionally.
All-in bundle: $217 first month, then $297/mo. 'bundle' in dose keeps it out of the molecule cost-engine so it does not double-count the standalone $151 med row.
All-in bundle: $349 first month, then $449/mo.
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Roen Rx
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
Roen Rx
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | Roen Rx |
|---|---|---|
| Starting Price | $100/mo | ✓$25/mo |
| Features | 6 features | ✓8 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About Roen Rx
Roen Rx offers compounded semaglutide as well as brand-name Ozempic, Wegovy, Zepbound, and Mounjaro with insurance coordination. LegitScript approved. Insurance-covered brand GLP-1s as low as $25/mo; compounded semaglutide from $151/mo quarterly.
Read our full Roen Rx review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Roen Rx
What we like
- Insurance coordination for brand-name GLP-1s — as low as $25/mo
- Both compounded and brand-name options
- LegitScript approved with Compounded USA badge
- Compounded semaglutide from $151/mo quarterly
- Also offers primary care, mental health, and other specialties
Watch-outs
- State availability not publicly disclosed
- Insurance coordination may not work for all plans
- Broader platform (ED, hair loss, skincare, birth control)
- Requires a separate membership (first month $39); GLP-1 medications are NOT included in the membership fee - medication is billed on top
Our Verdict
NewSelf edges out Roen Rx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Roen Rx remains a solid alternative, especially if you're looking for patients with insurance seeking brand-name GLP-1 access with compounded fallback.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose Roen Rx if…
You want patients with insurance seeking brand-name GLP-1 access with compounded fallback and a starting price around $25/mo.
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Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →MEDVi
Patients who want the option to switch between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →Liv Body
Compounded GLP-1 paired with a muscle-preservation supplement stack
From $179/mo
Get started →NewSelf vs Roen Rx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.