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NewSelf vs Renlo Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf
VS
Renlo Health logo

Renlo Health

7.8
★★★3.9/5

Best for: flat dose pricing with the pharmacy and medical group named

Visit Renlo Health

NewSelf and Renlo Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

Renlo Health

Once-weekly compounded injection, billed monthly (flat at every dose)Compounded
$199/mo
semaglutide

'$199/mo' against a struck-through '$299'; '$199 Starting dose / $199 Mid dose / $199 Higher dose'.

Once-weekly compounded injection, billed monthly (flat at every dose)Compounded
$269/mo
tirzepatide

'$269/mo' against a struck-through '$399'; 'Your price stays flat', '$0 increase, at every dose'.

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Renlo Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

Renlo Health

7.8/10

Value25%

9.0A
vs
B
7.5

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

8.3A
vs
B
7.8

Accessibility10%

8.5A
vs
B
8.5

Support10%

7.9A
vs
B
7.0

Features & Coverage

FeatureNewSelfRenlo Health
Starting Price$100/mo$199/mo
Features6 features7 features
States Available4950
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA Warnings1 warningNone

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About Renlo Health

Renlo Health is a telehealth platform selling compounded semaglutide at $199/mo and compounded tirzepatide at $269/mo, flat at every dose, with medication, injection supplies, provider care and expedited shipping in one monthly price and no membership fee. It names both its prescribing medical group and its dispensing pharmacy, and adds NAD+ and glutathione injections as separate longevity products.

Read our full Renlo Health review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Renlo Health

What we like

  • Flat pricing published before intake: semaglutide $199/mo, tirzepatide $269/mo, same price at every dose
  • Names its prescribing medical group (Arora Health & Aesthetics, LLC, Seattle) and its dispensing pharmacy (VialsRx, Houston)
  • Two named physicians front the clinical side, both identified by name and role
  • One price covers medication, injection supplies, provider evaluation, ongoing care and expedited shipping
  • No membership or consultation fee, and 'Cancel anytime, no fee'
  • LegitScript seal is served from LegitScript's own CDN, not self-hosted
  • You are only charged if a provider prescribes; not approved means a full refund

Watch-outs

  • Tirzepatide at $269/mo sits well above the compounded market's cheaper end
  • The four-month money-back guarantee is narrow — two timed weight verifications, unbroken enrollment, full adherence, and under 2% lost
  • Outside that guarantee 'all sales are final' — no returns on prescription products
  • No phone number is published; support is email only, despite a '24/7 concierge support' claim
  • The intake asks for your mobile number and opts you into SMS before it will go further
  • The all-50-states claim comes with a caveat that medications and fulfillment vary by state
  • Compounded semaglutide and tirzepatide are not FDA-approved

Our Verdict

Winner: NewSelf

NewSelf edges out Renlo Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Renlo Health remains a solid alternative, especially if you're looking for flat dose pricing with the pharmacy and medical group named.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose Renlo Health if…

You want flat dose pricing with the pharmacy and medical group named and a starting price around $199/mo.

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7.6

Maximus

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8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

6.9

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Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

NewSelf vs Renlo Health: FAQ

NewSelf is cheaper. Its lowest ongoing monthly cash price is $100/mo, compared with $199/mo for Renlo Health. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
NewSelf scores higher overall at 8.3/10 versus 7.8/10, and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. That said, Renlo Health is a better fit if you want flat dose pricing with the pharmacy and medical group named.
Renlo Health covers more — 50 states versus 49.
Neither NewSelf nor Renlo Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, NewSelf is cheaper at $100/mo versus $199/mo at Renlo Health.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring NewSelf and Renlo Health head-to-heads in the same category.

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