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NewSelf vs PrescribedRX

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf
VS
PrescribedRX logo

PrescribedRX

6.8
★★★☆☆3.4/5

Best for: people who want compounded GLP-1 weight loss inside a broader men's and women's telehealth brand

Visit PrescribedRX

NewSelf and PrescribedRX are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $189/mo, and NewSelf edges ahead overall (8.3 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

PrescribedRX

Injectablecompounded injection
$189/mo
semaglutide

Monthly plan $189/mo; as low as $176/mo on the 3-month plan ($526)

Injectablecompounded injection
$276/mo
tirzepatide

Monthly plan $276/mo; as low as $233/mo on the 3-month plan ($697)

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

PrescribedRX

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

PrescribedRX

6.8/10

Value25%

9.0A
vs
B
6.5

Effectiveness25%

8.0A
vs
B
7.0

User Experience15%

8.0A
vs
B
7.5

Trust & Safety15%

8.3A
vs
B
6.3

Accessibility10%

8.5A
vs
B
7.0

Support10%

7.9A
vs
B
6.9

Features & Coverage

FeatureNewSelfPrescribedRX
Starting Price$100/mo$189/mo
Features6 features8 features
States Available49Not disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About PrescribedRX

PrescribedRX is a multi-condition telehealth brand (TRT, longevity, hair loss, sexual health and weight loss) that prescribes compounded GLP-1 injectables for weight loss: semaglutide at $189/month and tirzepatide at $276/month, dropping to $176 and $233/month on a 3-month plan. Care is delivered online with licensed US-provider oversight and monthly home delivery, and the site is bilingual (English/Spanish) with Florida/Palm Beach-focused offers. It runs an in-house affiliate program but does not name its compounding pharmacies or publish the states it serves.

Read our full PrescribedRX review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

PrescribedRX

What we like

  • Compounded semaglutide ($189/mo) and tirzepatide ($276/mo) injectables, with lower per-month pricing on the 3-month plans ($176 and $233/mo)
  • Clear, upfront plan pages showing monthly and multi-month pricing with no surprise fees
  • Care from licensed US providers with monthly home delivery and ongoing dose support
  • Bilingual English/Spanish site and a broader telehealth menu (TRT, longevity, hair, sexual health) for people who want more than weight loss

Watch-outs

  • Doesn't publish the states it serves — you only learn eligibility after starting the intake
  • Compounding pharmacies aren't named on the site
  • Mid-range pricing — cheaper compounded GLP-1 options exist and the 3-month discount is modest
  • Compounded semaglutide and tirzepatide injectables only — no brand-name or oral options
  • Self-hosted affiliate program (not a vetted network); Florida/Palm Beach framing suggests a regional lean

Our Verdict

Winner: NewSelf

NewSelf edges out PrescribedRX with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. PrescribedRX remains a solid alternative, especially if you're looking for people who want compounded GLP-1 weight loss inside a broader men's and women's telehealth brand.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose PrescribedRX if…

You want people who want compounded GLP-1 weight loss inside a broader men's and women's telehealth brand and a starting price around $189/mo.

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NewSelf vs PrescribedRX: FAQ

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