NewSelf vs PauseRX
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
PauseRX
Best for: explicit 503A pharmacy and physician-network disclosure
Visit PauseRX →NewSelf and PauseRX are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 6.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
PauseRX
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
PauseRX
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
PauseRX
6.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | PauseRX |
|---|---|---|
| Starting Price | ✓$100/mo | $199/mo |
| Features | 6 features | ✓8 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About PauseRX
PauseRX is a nationwide compounded GLP-1 telehealth platform notable for its transparency: it names its 503A pharmacy partner (Strive Pharmacy in Gilbert, AZ), its physician network (Beluga Health), and publishes a full FDA compounded-medication disclaimer. Despite the name, it isn't menopause-specific. Compounded semaglutide is a flat $199/mo at all doses and tirzepatide starts at $249/mo, with brand Wegovy, Zepbound, and Foundayo also available.
Read our full PauseRX review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
PauseRX
What we like
- Names its 503A pharmacy partner (Strive Pharmacy, Gilbert AZ) — buyers can independently verify its licensure
- Names its physician network (Beluga Health) — you can research the clinical platform handling your prescriptions
- Publishes the FDA compounded-medication disclaimer
- Corporate legal entity disclosed (PauseRX, Inc.) — uncommon for direct-to-consumer GLP-1 platforms
- Flat $199 'all doses' compounded semaglutide pricing — no per-tier escalation
- Billed at ship, not at order — lower upfront cash exposure
- LegitScript badge displayed
- Adjunct longevity products (NAD+, Glutathione, Sermorelin) for a broader wellness stack
Watch-outs
- States served not listed — site claims nationwide, but you must contact support to confirm availability
- Restrictive cancellation policy — orders can't be changed or canceled once submitted, and medications can't be returned
- No named medical director (Beluga Health is the network, not a named MD)
- LegitScript certification number not shown — badge only, so no direct lookup
- Insurance not accepted — cash-pay only; HSA/FSA eligibility not confirmed
- Corporate physical address not provided
- Despite the 'Pause' name, not positioned as menopause-specific care
- Brand Wegovy, Zepbound, and Foundayo are consultations only, not direct dispensing
Our Verdict
NewSelf edges out PauseRX with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. PauseRX remains a solid alternative, especially if you're looking for explicit 503A pharmacy and physician-network disclosure.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose PauseRX if…
You want explicit 503A pharmacy and physician-network disclosure and a starting price around $199/mo.
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TrimRx
Best overall value
From $135/mo
Get started →Sprout Health
LegitScript-verified compounded GLP-1 via named pharmacies
From $149/mo
Get started →PeterMD
Men seeking flat-priced compounded GLP-1 access alongside TRT or peptide therapy
From $105/mo
Get started →NewSelf vs PauseRX: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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