Navio MD vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Navio MD
Best for: compounded tirzepatide with brand-name fallback across 48 states
Visit Navio MD →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Navio MD and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $189/mo, and NewSelf edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Navio MD
as low as $189/mo; tiered by dose
as low as $345/mo; brand price varies by dose
as low as $445/mo; tiered by dose
as low as $1,249/mo; tiered by dose
Ozempic as low as $345/mo (compounded tirzepatide $189/mo also offered)
NewSelf
All dosages same price
All dosages same price
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What’s included
Navio MD
Inclusions not disclosed.
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Navio MD
7.5/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Navio MD | NewSelf |
|---|---|---|
| Starting Price | $189/mo | ✓$100/mo |
| Features | 6 features | 6 features |
| States Available | 48 | ✓49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Navio MD
NavioMD offers compounded tirzepatide ($247/mo) plus brand-name Ozempic ($1,199/mo) and Mounjaro ($1,249/mo). LegitScript verified. Available in 48 states (not AL or MS). Same price at every dose. Also offers women's hormone optimization.
Read our full Navio MD review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Navio MD
What we like
- LegitScript verified with board-certified providers and US-licensed pharmacies
- Both compounded and brand-name options
- 48-state coverage
- Hours 9am–10pm EST Mon–Sun
- Transparent tiered pricing: you only pay for your current dose
Watch-outs
- Not available in Alabama and Mississippi
- Compounded option is tirzepatide only — no compounded semaglutide listed
- Also offers women's HRT (broader platform)
- Pricing is tiered by dose ('as low as'); the entry prices climb as your dose increases
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Navio MD with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Navio MD remains a solid alternative, especially if you're looking for compounded tirzepatide with brand-name fallback across 48 states.
Choose Navio MD if…
You want compounded tirzepatide with brand-name fallback across 48 states and a starting price around $189/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Synergy Rx
Broadest drug catalog in the Lion MD white-label cluster
From $199/mo
Get started →RxSpan MD
Shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
From $179/mo
Get started →Strut Health
Oral-lozenge compounded GLP-1 access
From $99/mo
Get started →Navio MD vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.