Amazon One Medical vs MedLeanRx
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.2 out of 10).
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Key differences
- Price
- Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; MedLeanRx $149/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- Amazon One Medical 50 states; MedLeanRx 1 state (only Amazon One Medical: Alabama, Alaska, Arizona and 46 more)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); MedLeanRx: medication, clinician visits, shipping
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
MedLeanRx
Best for Texas-only compounded semaglutide priced from the starting dose, plus brand options
semaglutide
$149
starting dose
Our score 7.2/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
MedLeanRx
Price
Semaglutide / month
Not listed
$149/mo
starting dose
Tirzepatide / month
Not listed
$269/mo
starting dose
Oral semaglutide / month
Not listed
$149/mo
starting dose
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
1 state
Oral option listed
Yes
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None ('no long-term contracts or cancellation fees')
Refunds
Not disclosed
No refunds: 'All sales are final' (strict no-refund policy in Terms)
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Show where they differ by stateHide state lists
Only Amazon One Medical (49 states)
- Alabama
- Alaska
- Arizona
- Arkansas
- California
- Colorado
- Connecticut
- Delaware
- Florida
- Georgia
- Hawaii
- Idaho
- Illinois
- Indiana
- Iowa
- Kansas
- Kentucky
- Louisiana
- Maine
- Maryland
- Massachusetts
- Michigan
- Minnesota
- Mississippi
- Missouri
- Montana
- Nebraska
- Nevada
- New Hampshire
- New Jersey
- New Mexico
- New York
- North Carolina
- North Dakota
- Ohio
- Oklahoma
- Oregon
- Pennsylvania
- Rhode Island
- South Carolina
- South Dakota
- Tennessee
- Utah
- Vermont
- Virginia
- Washington
- West Virginia
- Wisconsin
- Wyoming
Every dose and plan: Amazon One Medical · MedLeanRx
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which MedLeanRx doesn't price
- Serves 49 states that MedLeanRx doesn't
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose MedLeanRx if…
- Lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
- LegitScript seal displayed; named supervising physician (Dr. Johnson Uzor, MD)
What to weigh up
- Not available in 49 states that Amazon One Medical serves
- Texas only, not available in the other 49 states
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
MedLeanRx
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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Ro
FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Read full review →From $149/mo (+ required membership)
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo (+ required membership)
Get started →CoreAge Rx
Lowest-price compounded semaglutide and tirzepatide with one flat price at every dose
Read full review →From $79/mo (“starting at” price)
Get started →Amazon One Medical vs MedLeanRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Amazon One Medical and MedLeanRx head-to-heads in the same category.
- Amazon One Medical vs Vytora Health
- Amazon One Medical vs CoreAge Rx
- Amazon One Medical vs Collective
- MedLeanRx vs Vytora Health
Or see the full category ranking, or alternatives to Amazon One Medical and MedLeanRx.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.