MDLive vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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MDLive
Best for: Insured or employer-covered patients wanting GLP-1s within full primary care
Visit MDLive →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →MDLive and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts at $100/mo, and NewSelf edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
MDLive
Pricing not publicly listed.
NewSelf
All dosages same price
All dosages same price
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What’s included
MDLive
Inclusions not disclosed.
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MDLive
7.0/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | MDLive | NewSelf |
|---|---|---|
| Starting Price | — | $100/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About MDLive
MDLive (an Evernorth/Cigna company) is a large telehealth provider offering urgent care, primary care, dermatology and behavioral health. Anti-obesity GLP-1 medications such as Wegovy and Zepbound can be prescribed at the clinician's discretion during a Primary Care routine visit, not urgent care, and are excluded in Florida, Louisiana, Mississippi and New Jersey. MDLive reaches over 50 million people through health insurance and employer benefits but also allows out-of-pocket direct visits, so cost depends heavily on coverage rather than a single published cash price.
Read our full MDLive review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
MDLive
What we like
- Prescribes FDA-approved branded GLP-1s including Wegovy and Zepbound
- Covered through insurance and employer benefits for 50M-plus people
- Board-certified physicians averaging about 15 years of experience
- Part of Evernorth/Cigna, a large established healthcare organization
- Offers full primary care, not just a single weight-loss funnel
Watch-outs
- GLP-1s only at clinician discretion in a Primary Care routine visit
- Anti-obesity meds not available in FL, LA, MS or NJ
- Distributed mainly via insurers and employers; cost varies by plan
- No transparent published monthly cash price for GLP-1 care
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out MDLive with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. MDLive remains a solid alternative, especially if you're looking for Insured or employer-covered patients wanting GLP-1s within full primary care.
Choose MDLive if…
You want Insured or employer-covered patients wanting GLP-1s within full primary care.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →ShedRx
Mainstream telehealth GLP-1 access
From $149/mo
Get started →bmiMD
Mainstream telehealth GLP-1 access
From $99/mo
Get started →MDLive vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.