MangoRx vs SkinnyRx
In our scoring, SkinnyRx edges ahead overall (7.6 vs 5.5 out of 10), and SkinnyRx costs less for oral compounded semaglutide (about $1,200 a year less).
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Key differences
- Price
- SkinnyRx $199/mo vs MangoRx $299/mo for oral compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,200 a year less with SkinnyRx)
- Included
- MangoRx: medication, clinician visits; SkinnyRx: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: MangoRx none, SkinnyRx 1
MangoRx
Affiliate partnerBest for men's-health shoppers who want oral compounded semaglutide at one flat price across doses
Oral compounded semaglutide
$299
$269.10 first month
Our score 5.5/10
SkinnyRx
Affiliate partnerBest for compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
semaglutide
$149.25
Our score 7.6/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
MangoRx
SkinnyRx
Price
Oral semaglutide / month
$299/mo
$269.10 first month
Better on this row: $199/mo
Oral semaglutide / year (modeled)
$3,588
Better on this row: $2,388
Semaglutide / month
Not listed
$149.25/mo
Tirzepatide / month
Not listed
$224.25/mo
Brand Wegovy / Ozempic / month
Not listed
$1,400/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,400/mo
Coverage
Oral option listed
Yes
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits
Medication, clinician visits, shipping
Terms & safety
Price shown
Plan quoted after intake; a price is published
Plan quoted after intake; a price is published
Minimum commitment
None
Not disclosed
Refunds
Full refund if declined, else all sales final
90-day money-back guarantee
FDA warning letters
Better on this row: None on record
1 warning letter
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose MangoRx if…
- No FDA warning letters on record (SkinnyRx has 1)
- Men's-health telehealth that bundles GLP-1, TRT, ED, and hair care under one provider
What to weigh up
- About $1,200 a year more than SkinnyRx for oral compounded semaglutide
- GLP-1 formulary, pricing tiers, states served, and pharmacy partners not yet confirmed
Choose SkinnyRx if…
- About $1,200 a year less than MangoRx for oral compounded semaglutide at standing prices
- Lists compounded semaglutide, compounded tirzepatide and brand-name Wegovy / Ozempic, which MangoRx doesn't price
- Both semaglutide and tirzepatide available
What to weigh up
- 1 FDA warning letter on record
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MangoRx
5.5/10
SkinnyRx
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →MangoRx vs SkinnyRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.