MadeMed vs PlexusDx
In our scoring, MadeMed edges ahead overall (7.4 vs 7.0 out of 10).
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Key differences
- Price
- MadeMed $239/mo on a 6-month prepaid plan; PlexusDx $129/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- PlexusDx 50 states (MadeMed doesn't publish a state list)
- Included
- MadeMed: not stated; PlexusDx: medication, clinician visits

MadeMed
Affiliate partnerBest for compounded GLP-1 in both injection and oral forms
semaglutide
$239
on a 6-month prepaid plan
Our score 7.4/10
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
MadeMed
PlexusDx
Price
Semaglutide / month
$239/mo
on a 6-month prepaid plan
$129/mo
microdose plan
Semaglutide / year (modeled)
$2,868
$1,548
Tirzepatide / month
$399/mo
on a 6-month prepaid plan
$249/mo
starting dose
Tirzepatide / year (modeled)
$4,788
$2,988
Oral semaglutide / month
$219/mo
on a 6-month prepaid plan
Not listed
Oral tirzepatide / month
$299/mo
on a 6-month prepaid plan
Not listed
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Not listed
Included in the price
Not disclosed
Medication, clinician visits
Terms & safety
Price shown
Before intake
Before intake
Lab work
Not required
Not disclosed
Video visit
Not required
Not disclosed
Minimum commitment
6-month plan for the listed price
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 500+ providers' prices on their own sites and email you when tracked prices move.
Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose MadeMed if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which PlexusDx doesn't price
- LegitScript certification badge on the homepage
- Customer phone support published (1-800-582-1428) — uncommon vs chat-only competitors
What to weigh up
- Its $239/mo compounded semaglutide price needs a 6-month prepaid plan
- No published state list; confirm yours at signup
Choose PlexusDx if…
- Its $129/mo compounded semaglutide price needs no prepay; MadeMed's $239 needs a 6-month prepay
- Publishes its full state list (50 states)
- Optional Precision Peptide genetic panel adds a personalization angle
What to weigh up
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MadeMed
7.4/10
PlexusDx
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
From $249/mo
Get started →Ro
FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Read full review →From $149/mo (+ required membership)
Get started →ShedRx
Compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans
Read full review →From $299/mo (after intro offer)
Get started →MadeMed vs PlexusDx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring MadeMed and PlexusDx head-to-heads in the same category.
- MadeMed vs Amazon One Medical
- MadeMed vs Vytora Health
- MadeMed vs CoreAge Rx
- PlexusDx vs Amazon One Medical
- PlexusDx vs Vytora Health
- PlexusDx vs CoreAge Rx
Or see the full category ranking, or alternatives to MadeMed and PlexusDx.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.