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MadeMed vs PlexusDx

In our scoring, MadeMed edges ahead overall (7.4 vs 7.0 out of 10).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
MadeMed $239/mo on a 6-month prepaid plan; PlexusDx $129/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
Coverage
PlexusDx 50 states (MadeMed doesn't publish a state list)
Included
MadeMed: not stated; PlexusDx: medication, clinician visits

How we compare providers

MadeMed logo

MadeMed

Affiliate partner

Best for compounded GLP-1 in both injection and oral forms

semaglutide

$239/mo

on a 6-month prepaid plan

Our score 7.4/10

PlexusDx logo

PlexusDx

Affiliate partner

Best for nationwide compounded GLP-1 with optional genetic-test personalization

semaglutide

$129/mo

microdose plan

Our score 7.0/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

MadeMed

PlexusDx

Price

Semaglutide / month

$239/mo

on a 6-month prepaid plan

$129/mo

microdose plan

Semaglutide / year (modeled)

$2,868

$1,548

Tirzepatide / month

$399/mo

on a 6-month prepaid plan

$249/mo

starting dose

Tirzepatide / year (modeled)

$4,788

$2,988

Oral semaglutide / month

$219/mo

on a 6-month prepaid plan

Not listed

Oral tirzepatide / month

$299/mo

on a 6-month prepaid plan

Not listed

Coverage

State availability

List not published

50 states

Oral option listed

Yes

Not listed

Included in the price

Not disclosed

Medication, clinician visits

Terms & safety

Price shown

Before intake

Before intake

Lab work

Not required

Not disclosed

Video visit

Not required

Not disclosed

Minimum commitment

6-month plan for the listed price

Not disclosed

FDA warning letters

None on record

None on record

Provider facts checked

August 2026

August 2026

Every dose and plan: MadeMed · PlexusDx

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

MadeMed logo

Choose MadeMed if…

  • Lists oral compounded semaglutide and oral compounded tirzepatide, which PlexusDx doesn't price
  • LegitScript certification badge on the homepage
  • Customer phone support published (1-800-582-1428) — uncommon vs chat-only competitors

What to weigh up

  • Its $239/mo compounded semaglutide price needs a 6-month prepaid plan
  • No published state list; confirm yours at signup
PlexusDx logo

Choose PlexusDx if…

  • Its $129/mo compounded semaglutide price needs no prepay; MadeMed's $239 needs a 6-month prepay
  • Publishes its full state list (50 states)
  • Optional Precision Peptide genetic panel adds a personalization angle

What to weigh up

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

MadeMed

7.4/10

Overall

PlexusDx

7.0/10

Value25%

7.0A
vs
B
7.0

Effectiveness25%

8.0A
vs
B
7.0

User Experience15%

8.0A
vs
B
7.0

Trust & Safety15%

7.3A
vs
B
6.8

Accessibility10%

6.0A
vs
B
7.5

Support10%

7.5A
vs
B
6.5

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6.9

TMates

Nationwide compounded GLP-1 availability including Puerto Rico

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From $249/mo

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7.7

Ro

FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help

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From $149/mo (+ required membership)

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8.0

ShedRx

Compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans

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From $299/mo (after intro offer)

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MadeMed vs PlexusDx: FAQ

MadeMed scores higher overall at 7.4/10 versus 7.0/10, and is particularly strong for compounded GLP-1 in both injection and oral forms. That said, PlexusDx is a better fit if you want nationwide compounded GLP-1 with optional genetic-test personalization.
Both MadeMed and PlexusDx are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
MadeMed: $239 per month on a 6-month prepaid plan, about $2,868 a year. PlexusDx: $129, about $1,548 a year. Not like-for-like: one figure is a per-month price on a prepaid multi-month plan.
MadeMed doesn't publish a state list. PlexusDx publishes 50 states. Where a list isn't published, confirm your state during sign-up before paying.
MadeMed: cancel anytime — not disclosed; minimum commitment — 6-month plan for the listed price; early-cancellation fee — not disclosed. PlexusDx doesn't state its cancellation terms. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring MadeMed and PlexusDx head-to-heads in the same category.

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