Luma Health Co vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.1 out of 10), and Luma Health Co costs less for compounded semaglutide (about $768 a year less).
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Key differences
- Price
- Luma Health Co $115/mo vs Vytora Health $179/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $768 a year less with Luma Health Co)
- Coverage
- Luma Health Co 29 states + DC; Vytora Health 50 states + DC (only Vytora Health: Alabama, Alaska, Arkansas and 18 more)
- Included
- Luma Health Co: medication; Vytora Health: medication, clinician visits, shipping

Luma Health Co
Best for no-subscription compounded GLP-1s, discounted for first responders & teachers
semaglutide
$115
Our score 7.1/10

Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Luma Health Co
Vytora Health
Price
Semaglutide / month
Better on this row: $115/mo
$179/mo
Semaglutide / year (modeled)
Better on this row: $1,380
$2,148
Tirzepatide / month
Better on this row: $180/mo
$249/mo
Tirzepatide / year (modeled)
Better on this row: $2,160
$2,988
Brand Zepbound / Mounjaro / month
Not listed
$1,399/mo
Coverage
State availability
29 states + DC
50 states + DC
Brand-name access listed
Not listed
Zepbound / Mounjaro
Included in the price
Medication
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Video visit
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Not disclosed
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
October 2026
Show where they differ by stateHide state lists
Only Vytora Health (21 states)
- Alabama
- Alaska
- Arkansas
- California
- Georgia
- Indiana
- Kansas
- Kentucky
- Michigan
- Mississippi
- Missouri
- New Jersey
- North Carolina
- Ohio
- Oklahoma
- Pennsylvania
- South Carolina
- Tennessee
- Virginia
- West Virginia
- Wisconsin
Every dose and plan: Luma Health Co · Vytora Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose Luma Health Co if…
- About $768 a year less than Vytora Health for compounded semaglutide at standing prices
- No subscription, monthly fee or membership — a direct-to-patient model where you pay per medication, and follow-up visits are free
- Founded and led by a named family nurse practitioner (Tiffani McKnight, FNP-C) licensed across 30 states/DC
What to weigh up
- Not available in 21 states that Vytora Health serves
- Offers compounded retatrutide (labeled "RTT/GLP-3"), an investigational triple agonist not FDA-approved — a higher-risk, less-studied option

Choose Vytora Health if…
- Lists brand-name Zepbound / Mounjaro, which Luma Health Co doesn't price
- Serves 21 states that Luma Health Co doesn't
- Both compounded and brand-name options on one platform
What to weigh up
- About $768 a year more than Luma Health Co for compounded semaglutide
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Luma Health Co
7.1/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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From $219/mo
Get started →Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Luma Health Co vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.