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Luma Health Co vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Luma Health Co logo

Luma Health Co

7.1
★★★3.6/5

Best for: no-subscription compounded GLP-1s, free follow-ups and consult discounts for first responders and teachers

Visit Luma Health Co
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Luma Health Co and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $170/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Luma Health Co

Weekly injectionCompounded
$120/mo
semaglutide

Starting price; dose-dependent. Billed separately from a one-time initial consult fee, with no monthly subscription or membership.

Weekly injectionCompounded
$180/mo
tirzepatide

Starting price; dose-dependent.

Weekly injectionCompounded
$170/mo
retatrutide

Marketed on-site as "RTT (GLP-3)"; retatrutide is an investigational triple agonist that is not FDA-approved.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Luma Health Co

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Luma Health Co

7.1/10

Overall

NewSelf

8.3/10

Value25%

7.5A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.0A
vs
B
8.3

Accessibility10%

7.5A
vs
B
8.5

Support10%

7.5A
vs
B
7.9

Features & Coverage

FeatureLuma Health CoNewSelf
Starting Price$170/mo$100/mo
Features8 features6 features
States Available3049
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Luma Health Co

Luma Health Co is a nurse-practitioner-led virtual weight-loss and wellness clinic founded by Tiffani McKnight, FNP-C. It prescribes compounded semaglutide (from $120/mo), tirzepatide (from $180/mo) and retatrutide — marketed on-site as "RTT (GLP-3)" — from $170/mo, on a direct-to-patient model with no subscription or membership. Medication is billed separately from a one-time consult fee (free for first responders, teachers and nurses), and follow-up visits are free. Care is by virtual visit with lab review. Serves 30 states/DC; HSA/FSA and financing accepted, no insurance.

Read our full Luma Health Co review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Luma Health Co

What we like

  • Transparent, competitive pricing published up front — compounded semaglutide from $120/mo, tirzepatide from $180/mo, retatrutide from $170/mo
  • No subscription, monthly fee or membership — a direct-to-patient model where you pay per medication, and follow-up visits are free
  • Free initial consults for first responders, law enforcement, military, nurses and teachers ($0), and $25 for other healthcare workers
  • Founded and led by a named family nurse practitioner (Tiffani McKnight, FNP-C) licensed across 30 states/DC, with HIPAA-compliant virtual visits
  • HSA/FSA funds and financing accepted, with itemized invoices for HSA/FSA submission

Watch-outs

  • Offers compounded retatrutide (labeled "RTT/GLP-3"), an investigational triple agonist not FDA-approved — a higher-risk, less-studied option
  • Compounded medications only — no brand-name Wegovy, Zepbound or Ozempic — and compounded GLP-1s aren't FDA-reviewed or approved
  • No LegitScript certification shown and no compounding-pharmacy partner named, so the dispensing pharmacy can't be independently verified
  • Small, newly established founder-led practice with a thin website and limited public track record or third-party reviews
  • Medication prices are "starting at" and billed on top of a one-time consult fee, so the true first-month cost runs higher than the headline

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Luma Health Co with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Luma Health Co remains a solid alternative, especially if you're looking for no-subscription compounded GLP-1s, free follow-ups and consult discounts for first responders and teachers.

Choose Luma Health Co if…

You want no-subscription compounded GLP-1s, free follow-ups and consult discounts for first responders and teachers and a starting price around $170/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Luma Health Co vs NewSelf: FAQ

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